关键词: anemia anemia of chronic diseases antitubercular therapy (att) cytokines ferritin hepcidin iron therapy tuberculosis anemia anemia of chronic diseases antitubercular therapy (att) cytokines ferritin hepcidin iron therapy tuberculosis

来  源:   DOI:10.7759/cureus.27746   PDF(Pubmed)

Abstract:
Tuberculosis (TB) is an airborne illness that induces systemic inflammation. It often affects the lungs causing cough, fever, and chest pain. A commonly associated comorbid condition in TB is anemia. This review article has summarized various studies with an aim to gain a better understanding of pathogenesis and the role of cytokines that contribute to the development of anemia in TB. The study has gathered risk factors that enhance the likelihood of TB patients acquiring anemia. It has reviewed therapeutic modalities such as antitubercular therapy and iron therapy in an attempt to find which of them are effective in reducing the severity of anemia. This review article has also emphasized the importance of measuring hepcidin and ferritin and has touched upon the investigations that can be easily implemented.
摘要:
结核病(TB)是一种空气传播的疾病,可引起全身性炎症。它经常影响肺部引起咳嗽,发烧,和胸痛。结核病中常见的合并症是贫血。这篇综述文章总结了各种研究,旨在更好地了解结核病中贫血的发病机制和细胞因子的作用。该研究收集了增加结核病患者贫血可能性的风险因素。它已经回顾了治疗方式,例如抗结核治疗和铁治疗,以试图发现它们中的哪一种可有效降低贫血的严重程度。这篇综述文章还强调了测量铁调素和铁蛋白的重要性,并涉及了易于实施的研究。
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