OBJECTIVE: (i) To consider the relevance of the Consensus Principles in 2022 by reviewing current global approaches to rising AMR. A wide range of factors, such as antibiotic overuse, most recently seen in COVID-19 patients, are still driving rising AMR even though there has been a high-level international response to the AMR threat; and (ii) as an introduction to this Supplement, which reports the findings of analyses of how AMR is being addressed in nine disparate countries (Brazil, India, Kuwait, Mexico, Pakistan, Russia, Saudi Arabia, Türkiye and Vietnam). Understanding how these initiatives are being pursued in different countries helps identify areas where more information is needed.
CONCLUSIONS: Adherence to the Consensus Principles remains as important now as it was in 2002. Achieving appropriate antibiotic prescribing is a vital objective in order that the right patient receives the right antibiotics at the right time to ensure optimal clinical outcomes while at the same time helping to limit further increases in AMR.
目标:(i)通过审查当前全球AMR上升的方法,在2022年考虑共识原则的相关性。各种各样的因素,比如抗生素的过度使用,最近在COVID-19患者中发现,尽管国际上已经对AMR威胁做出了高级别反应,但仍在推动AMR上升;(ii)作为本补编的导言,报告了九个不同国家如何解决AMR的分析结果(巴西,印度,科威特,墨西哥,巴基斯坦,俄罗斯,沙特阿拉伯,蒂尔基耶和越南)。了解这些举措是如何在不同国家推行的,有助于确定需要更多信息的领域。
结论:遵守共识原则现在和2002年一样重要。实现适当的抗生素处方是一个至关重要的目标,以便正确的患者在正确的时间接受正确的抗生素,以确保最佳的临床结果,同时有助于限制AMR的进一步增加。