Abstract:
The congenital absence of major salivary glands, particularly the submandibular gland, is a rare condition. Although the etiology of aplasia is unknown, it is thought to occur owing to defects that emerge during early fetal development. Agenesis of 1 or more of the major salivary glands may occur alone or in association with other congenital anomalies. Very few cases of bilateral submandibular gland aplasia have been reported in the literature. Patients with this condition can be either symptomatic or asymptomatic. Due to the probability of there being additional anomalies, patients and their families should be carefully evaluated. We present the ultrasound and computed tomography findings for a case of bilateral submandibular gland aplasia that was detected incidentally. A review of the literature on major salivary gland aplasia was also conducted.
摘要:
主要唾液腺的先天性缺失,尤其是颌下腺,是一种罕见的情况。虽然发育不全的病因尚不清楚,它被认为是由于早期胎儿发育中出现的缺陷而发生的。一个或多个主要唾液腺的发育不全可能单独发生或与其他先天性异常有关。文献中很少报道双侧下颌下腺发育不全的病例。患有这种疾病的患者可以是有症状的或无症状的。由于存在额外异常的可能性,患者及其家属应仔细评估。我们介绍了偶然发现的双侧下颌下腺发育不全的超声和计算机断层扫描结果。还对主要唾液腺发育不全的文献进行了综述。