细胞周期由胰岛素样生长因子信号控制 : 在细胞生长和有丝分裂调节之间的十字路口。
关键词: (scavenger protein for IGF2 & mannose-6-phosphate) GF GH HybR HybR-A IGF-I/II: insulin like growth factor peptides IGF-Type I receptor gene IGF1R IGF1R/IR hybrid receptor IGF1R/IR-A IR (also InsR) IR isoform A (exon 11-) IR-A IRS Insulin-like growth factor receptor RTK growth factor growth hormone igf1/2 igf1r igf2r/m6pr/SpI2-6 insr insulin like growth factor genes insulin receptor gene insulin receptor protein insulin receptor substrate mTOR mTOR complex. additional acronyms are clarified in the text mTORC mammalian target of rapamycin property of a GF to increase growth (hypertrophy) and number (hyperplasia) of a target cell or tissue receptor tyrosine kinase trans-membrane high affinity IGF2 scavenger protein trophic (effect) type I (protein)
Mesh : Animals Humans Cell Cycle / genetics physiology Cell Cycle Checkpoints / genetics physiology Cell Proliferation Insulin-Like Growth Factor I / metabolism Mammals / metabolism Receptor, IGF Type 1 / genetics Receptor, Insulin / genetics metabolism Receptors, Somatomedin / genetics Somatomedins
来 源: DOI:10.1080/15384101.2022.2108117