关键词: alopecia areata collapse of hair follicle immune privilege compound betamethasone dermoscopy microneedling

Mesh : Alopecia Areata / drug therapy Betamethasone / therapeutic use Child, Preschool Hair Hair Follicle / pathology Humans

来  源:   DOI:10.3389/fimmu.2022.939077   PDF(Pubmed)

Abstract:
Alopecia areata (AA) is a common inflammatory, non-cicatricial hair loss. At present, it is considered that its pathogenesis is an autoimmune disease specific to hair follicle organs mediated by T cells under the combined action of genetic and environmental factors. Treatment is challenging for children with severe AA who are resistant or intolerant to conventional treatment.Here, we treated a 3-year-old child with severe AA with microneedling combined with compound betamethasone. After 6 months of treatment, the patient\'s condition was significantly improved, and most of the primary hair loss areas had hair regeneration.
摘要:
斑秃(AA)是一种常见的炎症性疾病,非瘢痕性脱发。目前,认为其发病机制是由T细胞在遗传和环境因素的共同作用下介导的毛囊器官特异性自身免疫性疾病。对于对常规治疗耐药或不耐受的重度AA患儿,治疗具有挑战性。这里,我们用微针联合复方倍他米松治疗了一名3岁的重度AA患儿。经过6个月的治疗,病人的病情有了明显改善,并且大多数原发性脱发区域都有头发再生。
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