PDF(Pubmed)
Abstract：
UNASSIGNED: Normative data for autonomic function tests (AFT) is not available for Indian population.
UNASSIGNED: The aim of the study was to establish normative data in AFT and its correlation with age, gender, and body mass index.
UNASSIGNED: The study was done on 254 healthy subjects of age ≥18 years. All AFTs were done in autonomic laboratory at the Department of Neurology, Christian Medical College and Hospital, Ludhiana. Cardiovascular tests (heart rate response to deep breathing, HR changes in Valsalva maneuver and head-up tilt test (HUT)) and quantitative sudomotor axon reflex testing (QSART) were performed in all the subjects. Fifty subjects underwent thermoregulatory sweat test (TST).
UNASSIGNED: The mean age (SD) of study participants was 43 (16.0) years (range 20-84), and 129 (50.8%) were men. The normative value range (2.5-97.5 percentile) for HR difference, E: I ratio, and Valsalva ratio (VR) was 3.5-47.0, 1.05-1.93, and 1.11-2.64, respectively, for all the subjects. HR difference and E: I ratio showed an significant inverse relation with age (r = -0.623 and r = -0.584, respectively). VR also showed an inverse relation with age (r = -0.575, P =< 0.001), and female had a lower value than male (1.63 vs 1.78, P =< 0.001). In QSART, mean (SD) sweat volume was higher in males 0.630 (0.230) compared to females 0.513 (0.132) for all sites, P < 0.001, and similar trend was noticed for sweat area in TST.
UNASSIGNED: Normative AFT data has been established for Indian population for the first time. The values are comparable to previously published studies.
UNASSIGNED: The aim of the study was to establish normative data in AFT and its correlation with age, gender, and body mass index.
UNASSIGNED: The study was done on 254 healthy subjects of age ≥18 years. All AFTs were done in autonomic laboratory at the Department of Neurology, Christian Medical College and Hospital, Ludhiana. Cardiovascular tests (heart rate response to deep breathing, HR changes in Valsalva maneuver and head-up tilt test (HUT)) and quantitative sudomotor axon reflex testing (QSART) were performed in all the subjects. Fifty subjects underwent thermoregulatory sweat test (TST).
UNASSIGNED: The mean age (SD) of study participants was 43 (16.0) years (range 20-84), and 129 (50.8%) were men. The normative value range (2.5-97.5 percentile) for HR difference, E: I ratio, and Valsalva ratio (VR) was 3.5-47.0, 1.05-1.93, and 1.11-2.64, respectively, for all the subjects. HR difference and E: I ratio showed an significant inverse relation with age (r = -0.623 and r = -0.584, respectively). VR also showed an inverse relation with age (r = -0.575, P =< 0.001), and female had a lower value than male (1.63 vs 1.78, P =< 0.001). In QSART, mean (SD) sweat volume was higher in males 0.630 (0.230) compared to females 0.513 (0.132) for all sites, P < 0.001, and similar trend was noticed for sweat area in TST.
UNASSIGNED: Normative AFT data has been established for Indian population for the first time. The values are comparable to previously published studies.
摘要：
■自主功能测试（AFT）的规范数据不适用于印度人口。
■这项研究的目的是建立AFT的规范数据及其与年龄的相关性，性别,和体重指数。
■这项研究是对254名年龄≥18岁的健康受试者进行的。所有的AFTs都是在神经内科的自主神经实验室完成的，基督教医学院和医院，卢迪亚娜.心血管检查（对深呼吸的心率反应，在所有受试者中进行了Valsalva动作和抬头倾斜测试（HUT）的HR变化）和定量sudomotor轴突反射测试（QSART）。50名受试者接受了体温调节汗液测试（TST）。
■研究参与者的平均年龄（SD）为43（16.0）岁（范围20-84），129人(50.8%)为男性。HR差异的标准值范围（2.5-97.5百分位数），E:I比,和Valsalva比值（VR）分别为3.5-47.0、1.05-1.93和1.11-2.64，对于所有的主题。HR差异和E：I比与年龄呈显着负相关（分别为r=-0.623和r=-0.584）。VR与年龄呈负相关(r=-0.575,P=<0.001),女性低于男性（1.63vs1.78，P=<0.001）。在QSART,男性的平均(SD)汗液量0.630(0.230)高于女性0.513(0.132)。P<0.001，TST中的汗液面积趋势相似。
■首次为印度人口建立了规范的AFT数据。这些值与以前发表的研究相当。
■这项研究的目的是建立AFT的规范数据及其与年龄的相关性，性别,和体重指数。
■这项研究是对254名年龄≥18岁的健康受试者进行的。所有的AFTs都是在神经内科的自主神经实验室完成的，基督教医学院和医院，卢迪亚娜.心血管检查（对深呼吸的心率反应，在所有受试者中进行了Valsalva动作和抬头倾斜测试（HUT）的HR变化）和定量sudomotor轴突反射测试（QSART）。50名受试者接受了体温调节汗液测试（TST）。
■研究参与者的平均年龄（SD）为43（16.0）岁（范围20-84），129人(50.8%)为男性。HR差异的标准值范围（2.5-97.5百分位数），E:I比,和Valsalva比值（VR）分别为3.5-47.0、1.05-1.93和1.11-2.64，对于所有的主题。HR差异和E：I比与年龄呈显着负相关（分别为r=-0.623和r=-0.584）。VR与年龄呈负相关(r=-0.575,P=<0.001),女性低于男性（1.63vs1.78，P=<0.001）。在QSART,男性的平均(SD)汗液量0.630(0.230)高于女性0.513(0.132)。P<0.001，TST中的汗液面积趋势相似。
■首次为印度人口建立了规范的AFT数据。这些值与以前发表的研究相当。
