Abstract：
The objective of the present review is to synthesize all available research on the association between mobility capacity and incident disability in non-disabled older adults. MEDLINE, EMBASE and CINAHL databases were searched without any limits or restrictions until February 2021. Published reports of longitudinal cohort studies that estimated a direct association between baseline mobility capacity, assessed with a standardized outcome assessment, and subsequent development of disability, including initially non-disabled older adults were included. The risk of bias was assessed using the Quality in Prognosis Studies (QUIPS) tool. Random-effect models were used to explore the objective. The certainty of evidence was assessed using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach. The main outcome measures were the pooled relative risks (RR) per one conventional unit per mobility assessment for incident disability. A total of 40 reports (85,515 participants at baseline) were included. For usual and fast gait speed, the RR per -0.1 m/s was 1.23 (95% CI: 1.18-1.28; 26,638 participants) and 1.28 (95% CI: 1.19-1.38; 8161 participants), respectively. Each point decrease in Short Physical Performance Battery score increased the risk of incident disability by 30% (RR = 1.30, 95% CI: 1.23-1.38; 9183 participants). The RR of incident disability by each second increase in Timed Up and Go test and Chair Rise Test performance was 1.15 (95% CI: 1.09-1.21; 30,426 participants) and 1.07 (95% CI: 1.04-1.10; 9450 participants), respectively. The review concludes that among community-dwelling non-disabled older adults, poor mobility capacity is a potent modifiable risk factor for incident disability. Mobility impairment should be mandated as a quality indicator of health for older people.
摘要：
本综述的目的是综合所有有关非残疾老年人行动能力与意外残疾之间关系的研究。MEDLINE,直到2021年2月，EMBASE和CINAHL数据库都没有任何限制或限制。已发表的纵向队列研究报告估计了基线移动能力之间的直接关联，用标准化的结果评估进行评估，以及随后的残疾发展，包括最初非残疾的老年人在内。使用预后研究质量（QUIPS）工具评估偏倚风险。随机效应模型用于探索目标。使用建议分级评估证据的确定性，评估,开发和评估(等级)方法。主要结果指标是针对意外残疾的每个流动性评估每个常规单位的汇总相对风险（RR）。共纳入40份报告（基线时85,515名参与者）。对于通常和快速的步态速度，每-0.1m/s的RR为1.23（95％CI：1.18-1.28；26,638名参与者）和1.28（95％CI：1.19-1.38；8161名参与者），分别。短体能电池得分每降低一点，残疾事件的风险就会增加30％（RR=1.30，95％CI：1.23-1.38；9183名参与者）。TimedUpandGotest和ChairRiseTest表现每秒增加的事件残疾RR为1.15（95％CI：1.09-1.21；30,426名参与者）和1.07（95％CI：1.04-1.10；9450名参与者），分别。审查得出的结论是，在社区居住的非残疾老年人中，行动不便是意外残疾的一个有效的可改变的风险因素。应将行动障碍作为老年人健康的质量指标。
