Abstract：
It is unclear whether people with dementia (PwD) have more negative attitudes toward own aging (ATOA) than people without dementia and what factors influence ATOA among PwD. We investigated whether PwD have more negative ATOA than individuals without dementia and whether cognition and dementia subtype are associated with ATOA in PwD.
Data from the IDEAL and PROTECT studies were used to compare ATOA between 1502 PwD (mean (SD) age = 76.3 (8.5)) and 6377 individuals without dementia (mean (SD) age = 66.1 (7.1)). Linear regressions and ANOVA were used.
PwD reported slightly more negative ATOA than people without dementia; this relationship disappeared after controlling for depression and self-rated health. In PwD more positive ATOA showed negligible associations with better general cognition, memory performance, verbal fluency, and visuospatial ability. However, after adjusting for covariates only better visuospatial ability predicted more positive ATOA. Additional analyses showed that before and after controlling for covariates, individuals with poorer self-reported visual acuity have more negative ATOA. Amongst dementia subtypes, people with Parkinson\'s disease dementia and dementia with Lewy bodies reported most negative ATOA.
ATOA between PwD and people without dementia do not differ. ATOA in PwD appear to be affected not by cognitive impairment but by other characteristics that vary across dementia subtypes. Among PwD, those with Parkinson\'s disease dementia and dementia with Lewy bodies may have higher risk of experiencing negative ATOA due to the motor and visual impairments that they experience.
Data from the IDEAL and PROTECT studies were used to compare ATOA between 1502 PwD (mean (SD) age = 76.3 (8.5)) and 6377 individuals without dementia (mean (SD) age = 66.1 (7.1)). Linear regressions and ANOVA were used.
PwD reported slightly more negative ATOA than people without dementia; this relationship disappeared after controlling for depression and self-rated health. In PwD more positive ATOA showed negligible associations with better general cognition, memory performance, verbal fluency, and visuospatial ability. However, after adjusting for covariates only better visuospatial ability predicted more positive ATOA. Additional analyses showed that before and after controlling for covariates, individuals with poorer self-reported visual acuity have more negative ATOA. Amongst dementia subtypes, people with Parkinson\'s disease dementia and dementia with Lewy bodies reported most negative ATOA.
ATOA between PwD and people without dementia do not differ. ATOA in PwD appear to be affected not by cognitive impairment but by other characteristics that vary across dementia subtypes. Among PwD, those with Parkinson\'s disease dementia and dementia with Lewy bodies may have higher risk of experiencing negative ATOA due to the motor and visual impairments that they experience.
摘要：
目前尚不清楚痴呆症患者（PwD）是否比非痴呆症患者对自身衰老（ATOA）有更多的消极态度，以及哪些因素会影响PwD中的ATOA。我们调查了PwD是否比没有痴呆的个体具有更多的阴性ATOA，以及PwD中的认知和痴呆亚型是否与ATOA相关。
来自IDEAL和PROTECT研究的数据用于比较1502PwD（平均（SD）年龄=76.3（8.5））和6377名无痴呆个体（平均（SD）年龄=66.1（7.1））之间的ATOA。使用线性回归和ANOVA。
PwD报告的ATOA阴性比没有痴呆症的人稍多；这种关系在控制抑郁症和自我评估健康后消失了。在PwD中，更积极的ATOA与更好的一般认知表现出微不足道的关联，内存性能,口语流利,和视觉空间能力。然而,调整协变量后，只有更好的视觉空间能力预测更积极的ATOA。额外的分析表明，在控制协变量之前和之后，自我报告视力较差的个体有更多的阴性ATOA。在痴呆症亚型中，帕金森病痴呆和路易体痴呆患者报告的ATOA阴性最多。
PwD和没有痴呆的人之间的ATOA没有区别。PwD中的ATOA似乎不受认知障碍的影响，而是受痴呆亚型不同的其他特征的影响。在PwD中,患有帕金森病痴呆和路易体痴呆的患者,由于他们所经历的运动和视觉障碍,可能有更高的风险经历负ATOA.
来自IDEAL和PROTECT研究的数据用于比较1502PwD（平均（SD）年龄=76.3（8.5））和6377名无痴呆个体（平均（SD）年龄=66.1（7.1））之间的ATOA。使用线性回归和ANOVA。
PwD报告的ATOA阴性比没有痴呆症的人稍多；这种关系在控制抑郁症和自我评估健康后消失了。在PwD中，更积极的ATOA与更好的一般认知表现出微不足道的关联，内存性能,口语流利,和视觉空间能力。然而,调整协变量后，只有更好的视觉空间能力预测更积极的ATOA。额外的分析表明，在控制协变量之前和之后，自我报告视力较差的个体有更多的阴性ATOA。在痴呆症亚型中，帕金森病痴呆和路易体痴呆患者报告的ATOA阴性最多。
PwD和没有痴呆的人之间的ATOA没有区别。PwD中的ATOA似乎不受认知障碍的影响，而是受痴呆亚型不同的其他特征的影响。在PwD中,患有帕金森病痴呆和路易体痴呆的患者,由于他们所经历的运动和视觉障碍,可能有更高的风险经历负ATOA.
