Abstract：
Introduction: The prevalence and patterns of sleep disturbances in neurocutaneous syndromes are variable and understudied. Methods: Cross-sectional study for 18 months at a tertiary care pediatric hospital, involving 100 children with neurocutaneous syndromes aged between 4 and 10 years using the Children\'s Sleep Habits Questionnaire-Abbreviated. Results: In 100 children with neurocutaneous syndromes, 47 (47%) had significant sleep problems. In subgroup analysis, 7 of 17 children with neurofibromatosis 1, 24 of 63 children with tuberous sclerosis complex, 10 of 12 children with Sturge-Weber syndrome, 2 of 3 children with linear nevus sebaceous syndrome, and each of the children with hypomelanosis of Ito, McCune-Albright syndrome, megalencephaly-capillary malformation syndrome, and unclassified neurocutaneous syndrome had significant sleep problems. Conclusion: The prevalence of sleep problems in our study population was not more than that observed in the general pediatric population. Prospective multicentric studies are needed to comprehend sleep problems in children with neurocutaneous syndromes.
摘要：
简介：神经皮肤综合征中睡眠障碍的患病率和模式是可变的，并且研究不足。方法：在三级护理儿科医院进行18个月的横断面研究，使用儿童睡眠习惯问卷-缩写，涉及100名年龄在4至10岁之间的神经皮肤综合征儿童。结果：在100名患有神经皮肤综合征的儿童中，47(47%)有显著的睡眠问题。在亚组分析中，17例神经纤维瘤病患儿中的7例1，63例结节性硬化症患儿中的24例，12名患有Sturge-Weber综合征的儿童中有10名，3例线性痣皮脂腺综合征患儿中的2例，每个患有伊藤黑色素减少症的孩子，McCune-Albright综合征,巨脑-毛细血管畸形综合征,未分类的神经皮肤综合征有明显的睡眠问题。结论：我们研究人群中睡眠问题的患病率不超过一般儿科人群。需要前瞻性的多中心研究来了解神经皮肤综合征儿童的睡眠问题。
