Abstract：
UNASSIGNED: The aim of the UVHER project is to evaluate the risk of development of optic nerve damage in patients with herpetic anterior uveitis (AU) prospectively followed over 2 years. Herein, we described the baseline characteristics.
UNASSIGNED: This is a multicentre, prospective study. An aqueous humour tap was performed. Only patients with a positive PCR were included. Clinical characteristics, optical coherence tomography (OCT) parameters and visual field (VF) abnormalities were registered.
UNASSIGNED: 27 patients were included: 18 Herpes Simplex (HSV), one Varicella Zoster (VVZ), and 8Cytomegalovirus (CMV). Patients with HSV-AU had severe inflammation, iris atrophy and corneal involvement. In patients with CMV-AU, less inflammation and medium-to-large keratic precipitates were observed. OCT showed a thinner RNFL and GCL in CMV-AU patients in comparison to HSV patients. VF showed abnormalities in six cases.
UNASSIGNED: Patients in the UVHER cohort showed the typical clinical manifestations of herpetic AU. In CMV patients, optic nerve damage was observed at baseline, and in HSV patients, inflammation was more severe.
UNASSIGNED: This is a multicentre, prospective study. An aqueous humour tap was performed. Only patients with a positive PCR were included. Clinical characteristics, optical coherence tomography (OCT) parameters and visual field (VF) abnormalities were registered.
UNASSIGNED: 27 patients were included: 18 Herpes Simplex (HSV), one Varicella Zoster (VVZ), and 8Cytomegalovirus (CMV). Patients with HSV-AU had severe inflammation, iris atrophy and corneal involvement. In patients with CMV-AU, less inflammation and medium-to-large keratic precipitates were observed. OCT showed a thinner RNFL and GCL in CMV-AU patients in comparison to HSV patients. VF showed abnormalities in six cases.
UNASSIGNED: Patients in the UVHER cohort showed the typical clinical manifestations of herpetic AU. In CMV patients, optic nerve damage was observed at baseline, and in HSV patients, inflammation was more severe.
摘要：
■UVHER项目的目的是评估前瞻性随访超过2年的疱疹性前葡萄膜炎（AU）患者发生视神经损伤的风险。在这里，我们描述了基线特征.
■这是一个多中心，前瞻性研究。进行水性幽默水龙头。仅包括PCR阳性的患者。临床特征,记录光学相干断层扫描(OCT)参数和视野(VF)异常.
■包括27例患者：18例单纯疱疹（HSV），一个水痘带状疱疹（VVZ），和8巨细胞病毒（CMV）。HSV-AU患者有严重的炎症,虹膜萎缩和角膜受累。在CMV-AU患者中，观察到较少的炎症和中等至较大的角膜沉淀。与HSV患者相比，OCT显示CMV-AU患者的RNFL和GCL较薄。6例VF显示异常。
■UVHER队列中的患者表现为典型的疱疹性AU临床表现。在CMV患者中，视神经损伤在基线观察，在HSV患者中，炎症更严重。
■这是一个多中心，前瞻性研究。进行水性幽默水龙头。仅包括PCR阳性的患者。临床特征,记录光学相干断层扫描(OCT)参数和视野(VF)异常.
■包括27例患者：18例单纯疱疹（HSV），一个水痘带状疱疹（VVZ），和8巨细胞病毒（CMV）。HSV-AU患者有严重的炎症,虹膜萎缩和角膜受累。在CMV-AU患者中，观察到较少的炎症和中等至较大的角膜沉淀。与HSV患者相比，OCT显示CMV-AU患者的RNFL和GCL较薄。6例VF显示异常。
■UVHER队列中的患者表现为典型的疱疹性AU临床表现。在CMV患者中，视神经损伤在基线观察，在HSV患者中，炎症更严重。
