Abstract：
UNASSIGNED: Ascertaining the role of cytokeratin-19 (CK19) and its staining pattern helps to differentiate papillary carcinoma from other thyroid lesions.
UNASSIGNED: To correlate fine needle aspiration cytology (FNAC) and cell block study of equivocal cases (Category III, IV, and V) with the role of CK19 staining in it.
UNASSIGNED: A hospital-based cross-sectional observational study was designed and conducted at North Bengal Medical College and Hospital, Shusrutnagar, Darjeeling.
UNASSIGNED: The FNAC performed and reported as per TBSRTC-2017.50 cases of Category III, IV, and V was selected for cell block study and CK19 staining followed by immunohistochemical scoring.
UNASSIGNED: Out of 50 cases, 17 were follicular neoplasm, 21 papillary carcinoma, 6 lymphocytic thyroiditis, 1 Hürthle cell adenoma, 1 medullary carcinoma, 1 lymphoma, and 3 undifferentiated carcinomas. Among cases of papillary carcinoma, 10 showed 4+ positivity, 9 showed 3+ positivity, 2 showed focal 1+ and 2+ positivity. In the case of follicular neoplasm, 1 showed 3+ positivity, 3 cases had 1+ 2+ positivity, and 13 cases revealed negative staining.
UNASSIGNED: Role of CK19 in distinguishing papillary carcinoma of thyroid from other lesions in cytologically diagnosed Category III, IV, and V (TBSRTC-2017) cases can be demonstrated.
UNASSIGNED: To correlate fine needle aspiration cytology (FNAC) and cell block study of equivocal cases (Category III, IV, and V) with the role of CK19 staining in it.
UNASSIGNED: A hospital-based cross-sectional observational study was designed and conducted at North Bengal Medical College and Hospital, Shusrutnagar, Darjeeling.
UNASSIGNED: The FNAC performed and reported as per TBSRTC-2017.50 cases of Category III, IV, and V was selected for cell block study and CK19 staining followed by immunohistochemical scoring.
UNASSIGNED: Out of 50 cases, 17 were follicular neoplasm, 21 papillary carcinoma, 6 lymphocytic thyroiditis, 1 Hürthle cell adenoma, 1 medullary carcinoma, 1 lymphoma, and 3 undifferentiated carcinomas. Among cases of papillary carcinoma, 10 showed 4+ positivity, 9 showed 3+ positivity, 2 showed focal 1+ and 2+ positivity. In the case of follicular neoplasm, 1 showed 3+ positivity, 3 cases had 1+ 2+ positivity, and 13 cases revealed negative staining.
UNASSIGNED: Role of CK19 in distinguishing papillary carcinoma of thyroid from other lesions in cytologically diagnosed Category III, IV, and V (TBSRTC-2017) cases can be demonstrated.
摘要：
■确定细胞角蛋白19（CK19）的作用及其染色模式有助于区分乳头状癌与其他甲状腺病变。
■为了将细针穿刺细胞学（FNAC）和可疑病例的细胞块研究（III类，IV,和V)具有CK19染色在其中的作用。
■在北孟加拉医学院和医院设计并进行了一项基于医院的横断面观察研究，Shusrutnagar,大吉岭.
■FNAC按照TBSRTC-2017.50的III类病例进行并报告，IV,选择V进行细胞块研究和CK19染色，然后进行免疫组织化学评分。
■在50例病例中，17是滤泡性肿瘤，21乳头状癌，6淋巴细胞性甲状腺炎，1Hürthle细胞腺瘤，1髓样癌，1淋巴瘤，和3个未分化癌。在乳头状癌的病例中，10显示4+阳性，9显示3+阳性，2显示病灶1+和2+阳性。在滤泡性肿瘤的情况下，1显示3+阳性，3例1+2+阳性，13例染色阴性。
■CK19在区分细胞学诊断为III类的甲状腺乳头状癌和其他病变中的作用，IV,可以证明V（TBSRTC-2017）病例。
■为了将细针穿刺细胞学（FNAC）和可疑病例的细胞块研究（III类，IV,和V)具有CK19染色在其中的作用。
■在北孟加拉医学院和医院设计并进行了一项基于医院的横断面观察研究，Shusrutnagar,大吉岭.
■FNAC按照TBSRTC-2017.50的III类病例进行并报告，IV,选择V进行细胞块研究和CK19染色，然后进行免疫组织化学评分。
■在50例病例中，17是滤泡性肿瘤，21乳头状癌，6淋巴细胞性甲状腺炎，1Hürthle细胞腺瘤，1髓样癌，1淋巴瘤，和3个未分化癌。在乳头状癌的病例中，10显示4+阳性，9显示3+阳性，2显示病灶1+和2+阳性。在滤泡性肿瘤的情况下，1显示3+阳性，3例1+2+阳性，13例染色阴性。
■CK19在区分细胞学诊断为III类的甲状腺乳头状癌和其他病变中的作用，IV,可以证明V（TBSRTC-2017）病例。
