PDF(Pubmed)
Abstract：
UNASSIGNED: Social cognition comprises basic and more complex functions, such as theory of mind (ToM) and affective empathy. Although everyday social interactions may be impaired if such higher-order social cognitive functions are compromised, associations between social functioning and social cognition in people with focal epilepsy (PWFE) are still poorly understood. We used a novel, naturalistic approach to investigate ToM in PWFE by applying the Movie for the Assessment of Social Cognition (MASC). Furthermore, we studied affective empathy, the relationship between social cognitive parameters and measures of social functioning, as well as between epilepsy focus and ToM.
UNASSIGNED: Thirty patients with either temporal (TLE) or frontal lobe epilepsy (FLE) were compared to 29 healthy control subjects (HC). In addition to the MASC, we applied questionnaire measures assessing empathy and everyday social functioning.
UNASSIGNED: PWFE, especially with FLE, performed significantly worse than HC on the MASC. Perceived social integration and social activities, but not affective empathy, were reduced in PWFE. Regression analyses revealed associations between perceived social integration, clinical group status, affective empathy and ToM.
UNASSIGNED: PWFE displayed ToM deficits during a naturalistic task, whereas affective empathy was unimpaired. FLE may be associated with especially compromised ToM performance. Social cognition and social functioning appear to be interrelated in PWFE, whose self-perceived levels of social integration and social activities are lower than those of HC. More research into the association between social cognition and social functioning in PWFE is needed, in order to develop tailored intervention programs for these patients.
UNASSIGNED: Thirty patients with either temporal (TLE) or frontal lobe epilepsy (FLE) were compared to 29 healthy control subjects (HC). In addition to the MASC, we applied questionnaire measures assessing empathy and everyday social functioning.
UNASSIGNED: PWFE, especially with FLE, performed significantly worse than HC on the MASC. Perceived social integration and social activities, but not affective empathy, were reduced in PWFE. Regression analyses revealed associations between perceived social integration, clinical group status, affective empathy and ToM.
UNASSIGNED: PWFE displayed ToM deficits during a naturalistic task, whereas affective empathy was unimpaired. FLE may be associated with especially compromised ToM performance. Social cognition and social functioning appear to be interrelated in PWFE, whose self-perceived levels of social integration and social activities are lower than those of HC. More research into the association between social cognition and social functioning in PWFE is needed, in order to develop tailored intervention programs for these patients.
摘要：
■社会认知包括基本和更复杂的功能，如心理理论(ToM)和情感移情。尽管如果这种高阶社会认知功能受损，日常社交互动可能会受到损害，对于局灶性癫痫(PWFE)患者的社会功能和社会认知之间的关联仍然知之甚少.我们用了一本小说,通过将电影应用于社会认知评估（MASC）来研究PWFE中的ToM的自然主义方法。此外，我们研究了情感移情，社会认知参数与社会功能测量之间的关系，以及癫痫焦点和ToM之间。
■将30名颞叶（TLE）或额叶癫痫（FLE）患者与29名健康对照受试者（HC）进行了比较。除了MASC,我们采用问卷调查法评估同理心和日常社会功能.
■PWFE，尤其是FLE，在MASC上的表现明显比HC差。感知到的社会融合和社会活动，但不是情感上的同理心，在PWFE中减少。回归分析揭示了感知的社会融合之间的关联，临床组状态，情感移情和ToM。
■PWFE在自然任务期间显示了ToM赤字，而情感移情没有受损。FLE可能与特别受损的ToM性能相关联。在PWFE中，社会认知和社会功能似乎是相互关联的，其自我感知的社会融合和社会活动水平低于HC。需要对PWFE中社会认知与社会功能之间的关联进行更多研究，以便为这些患者制定量身定制的干预计划。
■将30名颞叶（TLE）或额叶癫痫（FLE）患者与29名健康对照受试者（HC）进行了比较。除了MASC,我们采用问卷调查法评估同理心和日常社会功能.
■PWFE，尤其是FLE，在MASC上的表现明显比HC差。感知到的社会融合和社会活动，但不是情感上的同理心，在PWFE中减少。回归分析揭示了感知的社会融合之间的关联，临床组状态，情感移情和ToM。
■PWFE在自然任务期间显示了ToM赤字，而情感移情没有受损。FLE可能与特别受损的ToM性能相关联。在PWFE中，社会认知和社会功能似乎是相互关联的，其自我感知的社会融合和社会活动水平低于HC。需要对PWFE中社会认知与社会功能之间的关联进行更多研究，以便为这些患者制定量身定制的干预计划。
