Abstract：
Pulmonary Alveolar Proteinosis (PAP) is a rare, usually autoimmune, disease, where surfactant accumulates within alveoli due to decreased clearance, causing dyspnea and hypoxemia. The disease is even more rare in pregnancy; nevertheless, it has been reported in pregnant women and can even appear for the first time during pregnancy as an asthma-like illness. Therefore, awareness is important. Similarly to many autoimmune diseases, it can worsen during pregnancy and postpartum, causing maternal and fetal/neonatal complications. This paper offers a narrative literature review of PAP and pregnancy, while illustrating a case of a pregnant patient with known PAP who developed preeclampsia in the third trimester but had an overall fortunate maternal and neonatal outcome.
摘要：
肺泡蛋白沉积症（PAP）是一种罕见的，通常是自身免疫，疾病,表面活性剂由于清除减少而在肺泡内积聚，引起呼吸困难和低氧血症。这种疾病在怀孕期间更加罕见；尽管如此，据报道，它在孕妇中，甚至可以在怀孕期间首次出现哮喘样疾病。因此,意识很重要。类似于许多自身免疫性疾病，它会在怀孕和产后恶化，引起母体和胎儿/新生儿并发症。本文提供了关于PAP和怀孕的叙述性文献综述，同时说明了一例已知PAP的孕妇，该患者在妊娠晚期出现先兆子痫，但总体上孕产妇和新生儿结局幸运。
