{Reference Type}: Case Reports
{Title}: Pulmonary Alveolar Proteinosis and Pregnancy: A Review of the Literature and Case Presentation.
{Author}: Cimpoca Raptis BA;Panaitescu AM;Peltecu G;Gica N;Botezatu R;Popescu MR;Macri A;Constantin A;Pavel B;Cimpoca Raptis BA;Panaitescu AM;Peltecu G;Gica N;Botezatu R;Popescu MR;Macri A;Constantin A;Pavel B;Cimpoca Raptis BA;Panaitescu AM;Peltecu G;Gica N;Botezatu R;Popescu MR;Macri A;Constantin A;Pavel B;Cimpoca Raptis BA;Panaitescu AM;Peltecu G;Gica N;Botezatu R;Popescu MR;Macri A;Constantin A;Pavel B;
{Journal}: Medicina (Kaunas)
{Volume}: 58
{Issue}: 8
{Year}: Jul 2022 23
{Factor}: 2.948
{DOI}: 10.3390/medicina58080984
{Abstract}: Pulmonary Alveolar Proteinosis (PAP) is a rare, usually autoimmune, disease, where surfactant accumulates within alveoli due to decreased clearance, causing dyspnea and hypoxemia. The disease is even more rare in pregnancy; nevertheless, it has been reported in pregnant women and can even appear for the first time during pregnancy as an asthma-like illness. Therefore, awareness is important. Similarly to many autoimmune diseases, it can worsen during pregnancy and postpartum, causing maternal and fetal/neonatal complications. This paper offers a narrative literature review of PAP and pregnancy, while illustrating a case of a pregnant patient with known PAP who developed preeclampsia in the third trimester but had an overall fortunate maternal and neonatal outcome.