Abstract：
OBJECTIVE: The aim of the study was to compare and evaluate the utility of three different risk stratification scores for gastroschisis neonates; simple/complex gastroschisis, gastroschisis prognostic score and risk stratification index.
METHODS: Data of neonates born with gastroschisis between the years 1993 and 2015 were collected. The national registers and patient records of four Finnish University Hospitals were retrospectively reviewed. Logistic and linear regression analysis were performed to identify independent predictors for adverse outcomes. The efficacy of these prognostic methods was further assessed using ROC-curves and DeLong (1988) test.
RESULTS: Gastroschisis risk stratification index was an acceptable predictor of in-hospital mortality, AUC 0.70, 95% CI 0.48-0.91, p = 0.049. Complex gastroschisis and gastroschisis prognostic score were able to predict short bowel syndrome, AUC 0.80, 95% CI 0.58-1.00, p = 0.012 and AUC 0.80, 95% CI 0.59-1.00, p = 0.012, respectively.
CONCLUSIONS: There are three easily obtainable risk stratification scores for outcome prediction in gastroschisis patients, however, their predictive ability did not have a statistical difference in the present study. The Gastroschisis risk stratification index seemed to perform moderately well in mortality prediction.
METHODS: Data of neonates born with gastroschisis between the years 1993 and 2015 were collected. The national registers and patient records of four Finnish University Hospitals were retrospectively reviewed. Logistic and linear regression analysis were performed to identify independent predictors for adverse outcomes. The efficacy of these prognostic methods was further assessed using ROC-curves and DeLong (1988) test.
RESULTS: Gastroschisis risk stratification index was an acceptable predictor of in-hospital mortality, AUC 0.70, 95% CI 0.48-0.91, p = 0.049. Complex gastroschisis and gastroschisis prognostic score were able to predict short bowel syndrome, AUC 0.80, 95% CI 0.58-1.00, p = 0.012 and AUC 0.80, 95% CI 0.59-1.00, p = 0.012, respectively.
CONCLUSIONS: There are three easily obtainable risk stratification scores for outcome prediction in gastroschisis patients, however, their predictive ability did not have a statistical difference in the present study. The Gastroschisis risk stratification index seemed to perform moderately well in mortality prediction.
摘要：
目的：该研究的目的是比较和评估三种不同的风险分层评分对新生儿胃裂的效用；简单/复杂胃裂，腹裂预后评分和危险分层指数。
方法：收集1993年至2015年腹裂新生儿的数据。对四所芬兰大学医院的国家登记册和患者记录进行了回顾性审查。进行Logistic和线性回归分析以确定不良结局的独立预测因子。使用ROC曲线和DeLong(1988)检验进一步评估这些预后方法的功效。
结果：胃裂危险分层指数是住院死亡率的可接受预测指标，AUC0.70，95%CI0.48-0.91，p=0.049。复杂性腹裂和腹裂预后评分能够预测短肠综合征，AUC0.80,95%CI0.58-1.00,p=0.012,AUC0.80,95%CI0.59-1.00,p=0.012。
结论：有三个容易获得的风险分层评分用于胃裂患者的预后预测，然而,他们的预测能力在本研究中没有统计学差异.胃裂风险分层指数在死亡率预测中似乎表现良好。
方法：收集1993年至2015年腹裂新生儿的数据。对四所芬兰大学医院的国家登记册和患者记录进行了回顾性审查。进行Logistic和线性回归分析以确定不良结局的独立预测因子。使用ROC曲线和DeLong(1988)检验进一步评估这些预后方法的功效。
结果：胃裂危险分层指数是住院死亡率的可接受预测指标，AUC0.70，95%CI0.48-0.91，p=0.049。复杂性腹裂和腹裂预后评分能够预测短肠综合征，AUC0.80,95%CI0.58-1.00,p=0.012,AUC0.80,95%CI0.59-1.00,p=0.012。
结论：有三个容易获得的风险分层评分用于胃裂患者的预后预测，然而,他们的预测能力在本研究中没有统计学差异.胃裂风险分层指数在死亡率预测中似乎表现良好。
