An Unusual Presentation of Vitamin B12 Deficiency Associated With Massive Splenomegaly, Hemolytic Anemia, and Pancytopenia: A Case Report.

与大量脾肿大相关的维生素 B12 缺乏的异常呈现 ，溶血性贫血,全血细胞减少症 1 例.

• 发表时间: Jun 2022
• 来源期刊: Cureus
• DOI: 10.7759/cureus.26058
• PMID: 35865441
• 文章类型: Case Reports
• 作者列表: Elhiday H,Musa M,Hussaini SA,Al-Warqi A,Alfitori G,Elhiday H,Musa M,Hussaini SA,Al-Warqi A,Alfitori G

关键词: hemolytic anemia; massive splenomegaly; megaloblastic anemia; pancytopenia; splenomegaly; vitamin b12; vitamin b12 deficiency; hemolytic anemia; massive splenomegaly; megaloblastic anemia; pancytopenia; splenomegaly; vitamin b12; vitamin b12 deficiency

Abstract

Deficiency of vitamin B12 usually presents with symptoms of anaemia or neurological dysfunction. We report a case of a young lady who was found to be vitamin B12 deficient with massive splenomegaly, haemolytic anaemia, and pancytopenia. She was thoroughly investigated for other causes of similar presentation. Her symptoms and blood count drastically improved after two weeks of therapy with vitamin B12 supplementation. After reviewing the literature on unusual cases of vitamin B12 deficiency, our case is a very interesting read as it serves as a reminder for health care providers to be alert for these manifestations, which can be treated by simply replacing vitamin B12.

摘要

维生素B12缺乏通常表现为贫血或神经功能障碍的症状。我们报告了一个年轻女士的病例，她被发现缺乏维生素B12并伴有大量脾肿大，溶血性贫血,和全血细胞减少症.她被彻底调查了类似陈述的其他原因。在补充维生素B12治疗两周后，她的症状和血细胞计数显著改善。在回顾了有关维生素B12缺乏的异常病例的文献后，我们的案例是一个非常有趣的读物，因为它提醒医疗保健提供者对这些表现保持警惕，可以通过简单地替代维生素B12来治疗。