关键词: Abdominal wall CCC, clear cell carcinoma Caesarean section Case report Clear cell carcinoma Endometriosis Malignant transformation Abdominal wall CCC, clear cell carcinoma Caesarean section Case report Clear cell carcinoma Endometriosis Malignant transformation

来  源:   DOI:10.1016/j.amsu.2022.104038   PDF(Pubmed)

Abstract:
UNASSIGNED: Clear cell carcinoma of abdominal wall is a very rare and aggressive disease. It is mostly related to malignant transformation of abdominal wall endometriosis. This paper provides a new case report and a literature review of primitive abdominal wall clear cell carcinoma.
UNASSIGNED: A 45-year-old woman with a history of a two previous caesarian section presented to the outpatient department with a tumor mass evolving since 10 years in the lower right quadrant of her abdomen. Imaging studies revealed a voluminous subcutaneous mass developing at the expense of the anterior abdominal wall. Surgical resection of the mass was performed. Histopathological examination along with immunohistochemical analysis were consistent with clear cell carcinoma. Biopsies of the endometrium and ovaries were performed and were negative for malignancy. The patient underwent therefore a hysterectomy with bilateral salpingo-oophorectomy which did not reveal any disease. The diagnosis of primitive clear cell carcinoma of the abdominal wall was then confirmed.
UNASSIGNED: Primitive clear cell carcinoma of the abdominal wall is an extremely rare form of cancer with usually poor prognosis. Clinicians must be aware of the possibility of malignancy of any swelling mass occurring near or within a caesarean section scar.
UNASSIGNED: Reporting more such cases is still needed to further progress in the understanding of this malignancy in addition to the development of treatment strategies.
摘要:
腹壁透明细胞癌是一种非常罕见且侵袭性的疾病。多半与腹壁子宫内膜异位症的恶变有关。本文提供了1例新的原始腹壁透明细胞癌的病例报告和文献复习。
一名45岁女性,有两次剖腹产史,她的腹部右下象限有一个肿瘤肿块,从10年开始在门诊就诊。影像学研究显示,大量皮下肿块以前腹壁为代价发展。对肿块进行手术切除。组织病理学检查以及免疫组织化学分析与透明细胞癌一致。对子宫内膜和卵巢进行活检,检查结果为恶性肿瘤。因此,患者接受了子宫切除术和双侧输卵管卵巢切除术,未发现任何疾病。然后确认腹壁原始透明细胞癌的诊断。
腹壁原始透明细胞癌是一种极为罕见的癌症,通常预后较差。临床医生必须意识到剖腹产疤痕附近或内部发生的任何肿胀肿块的恶性肿瘤的可能性。
除了制定治疗策略外,仍需要报告更多此类病例以进一步了解这种恶性肿瘤。
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