PDF(Pubmed)
Abstract：
BACKGROUND: Providencia rettgeri is a rare cause of nosocomial infection in humans. These organisms are capable of biofilm production and are intrinsically resistant to commonly used antibiotics, leading to high rates of morbidity and mortality. P. rettgeri may very rarely cause postneurosurgical infection.
METHODS: In this report, the authors describe two patients in whom P. rettgeri infection complicated the postoperative course. Both the patients underwent craniotomy at approximately the same time under similar environments. The organism isolated was resistant to most of the commonly used antibiotics, and therapy tailored to the results of susceptibility testing led to resolution of infection in both cases.
CONCLUSIONS: P. rettgeri is a rare cause of postneurosurgical nosocomial infection. Timely identification and early tailoring of antibiotic therapy based on susceptibility testing is the key to treatment. Every effort should be made to identify the source of infection and rectify it so that mortality, morbidity, and financial burden are reduced. Contact isolation and use of sterile gloves after each patient contact are effective in preventing its spread, as in most cases of nosocomial infection.
METHODS: In this report, the authors describe two patients in whom P. rettgeri infection complicated the postoperative course. Both the patients underwent craniotomy at approximately the same time under similar environments. The organism isolated was resistant to most of the commonly used antibiotics, and therapy tailored to the results of susceptibility testing led to resolution of infection in both cases.
CONCLUSIONS: P. rettgeri is a rare cause of postneurosurgical nosocomial infection. Timely identification and early tailoring of antibiotic therapy based on susceptibility testing is the key to treatment. Every effort should be made to identify the source of infection and rectify it so that mortality, morbidity, and financial burden are reduced. Contact isolation and use of sterile gloves after each patient contact are effective in preventing its spread, as in most cases of nosocomial infection.
摘要：
背景：Providenciarettgeri是人类医院感染的罕见原因。这些生物能够产生生物膜，并且对常用的抗生素具有内在抗性，导致高发病率和死亡率。P.rettgeri很少引起神经外科术后感染。
方法：在本报告中，作者描述了两名患者，其中P.rettgeri感染使术后过程复杂化。两名患者在相似的环境下几乎同时进行了开颅手术。分离出的微生物对大多数常用的抗生素具有抗性，并且针对药敏试验结果的治疗导致两种情况下感染的解决。
结论：P.rettgeri是神经外科术后医院感染的罕见原因。根据药敏试验及时识别和早期定制抗生素治疗是治疗的关键。应尽一切努力查明感染源并加以纠正,发病率，减轻了财政负担。接触隔离并在每次患者接触后使用无菌手套可有效防止其传播，与大多数医院感染一样。
方法：在本报告中，作者描述了两名患者，其中P.rettgeri感染使术后过程复杂化。两名患者在相似的环境下几乎同时进行了开颅手术。分离出的微生物对大多数常用的抗生素具有抗性，并且针对药敏试验结果的治疗导致两种情况下感染的解决。
结论：P.rettgeri是神经外科术后医院感染的罕见原因。根据药敏试验及时识别和早期定制抗生素治疗是治疗的关键。应尽一切努力查明感染源并加以纠正,发病率，减轻了财政负担。接触隔离并在每次患者接触后使用无菌手套可有效防止其传播，与大多数医院感染一样。
