Abstract：
OBJECTIVE: Syphilis is a sexually transmitted infection (STI) caused by treponema pallidum. Its rash usually affects the trunk and limbs extensively, including the palms and soles of the feet. Secondary syphilis confined to the face is extremely rare.
METHODS: We report a case of annular rupioid secondary syphilis, which was misdiagnosed as verruca vulgaris.
RESULTS: The patient\'s lesions were confined to the face and resembled oyster shells. Her serological tests results were positive for treponema pallidum particle agglutination assay (TPPA) and rapid plasma reagin (RPR) (1:64).
CONCLUSIONS: According to epidemiological history, clinical presentation, non-treponemal tests, treponemal tests, and effective benzathine penicillin G treatment, confirmed secondary syphilis.
METHODS: We report a case of annular rupioid secondary syphilis, which was misdiagnosed as verruca vulgaris.
RESULTS: The patient\'s lesions were confined to the face and resembled oyster shells. Her serological tests results were positive for treponema pallidum particle agglutination assay (TPPA) and rapid plasma reagin (RPR) (1:64).
CONCLUSIONS: According to epidemiological history, clinical presentation, non-treponemal tests, treponemal tests, and effective benzathine penicillin G treatment, confirmed secondary syphilis.
摘要：
目的：梅毒是由梅毒螺旋体引起的性传播感染（STI）。它的皮疹通常广泛影响躯干和四肢，包括手掌和脚底.局限于面部的二期梅毒极为罕见。
方法：我们报告一例环状ruppioid二期梅毒，误诊为寻常疣.
结果：患者的病变局限于面部，类似牡蛎壳。她的血清学测试结果对梅毒螺旋体颗粒凝集测定（TPPA）和快速血浆反应素（RPR）（1：64）呈阳性。
结论：根据流行病学史，临床表现,非密螺旋体试验,密螺旋体试验,和有效的苄星青霉素G治疗，确诊为二期梅毒。
方法：我们报告一例环状ruppioid二期梅毒，误诊为寻常疣.
结果：患者的病变局限于面部，类似牡蛎壳。她的血清学测试结果对梅毒螺旋体颗粒凝集测定（TPPA）和快速血浆反应素（RPR）（1：64）呈阳性。
结论：根据流行病学史，临床表现,非密螺旋体试验,密螺旋体试验,和有效的苄星青霉素G治疗，确诊为二期梅毒。
