Abstract:
Helicobacter pylori infection is very common and affects more than one-third of adults in Italy. Helicobacter pylori causes several gastro-duodenal diseases, such as gastritis, peptic ulcer and gastric malignancy, and extra-gastric diseases. The eradication of the bacteria is becoming complex to achieve due to increasing antimicrobial resistance. To address clinical questions related to the diagnosis and treatment of Helicobacter pylori infection, three working groups examined the following topics: (1) non-invasive and invasive diagnostic tests, (2) first-line treatment, and (3) rescue therapies for Helicobacter pylori infection. Recommendations are based on the best available evidence to help physicians manage Helicobacter pylori infection in Italy, and have been endorsed by the Italian Society of Gastroenterology and the Italian Society of Digestive Endoscopy.
摘要:
幽门螺杆菌感染非常常见,影响意大利超过三分之一的成年人。幽门螺杆菌会导致几种胃十二指肠疾病,如胃炎,消化性溃疡和胃恶性肿瘤,和胃外疾病。由于抗微生物耐药性的增加,细菌的根除变得越来越复杂。为了解决与幽门螺杆菌感染的诊断和治疗有关的临床问题,三个工作组研究了以下主题:(1)非侵入性和侵入性诊断测试,(2)一线治疗,(3)幽门螺杆菌感染的抢救治疗。建议是基于最好的证据,以帮助医生管理意大利的幽门螺杆菌感染,并得到了意大利胃肠病学会和意大利消化内镜学会的认可。