PDF(Pubmed)
Abstract：
UNASSIGNED: There was a reorganization of the brain network after stroke. Some studies have compared the characteristics of activation or functional connectivity (FC) of cortical and subcortical regions between the dominant and non-dominant hemisphere stroke.
UNASSIGNED: To analyze hemispheric dominance differences in task-state motor network properties in subacute stroke by functional near-infrared spectroscopy (fNIRS).
UNASSIGNED: Patients with first ischemic stroke in the basal ganglia within 1-3 months after onset and age- and sex-matched right-handed healthy subjects (HS) were enrolled. fNIRS with 29 channels was used to detect the oxyhemoglobin concentration changes when performing the hand grasping task. Activation patterns of motor cortex and two macroscale and two mesoscale brain network indicators based on graph theory were compared between dominant and non-dominant hemisphere stroke.
UNASSIGNED: We enrolled 17 subjects in each of left hemisphere stroke (LHS), right hemisphere stroke (RHS), and HS groups. Both patient groups showed bilateral activation. The average weighted clustering coefficient and global efficiency of patients were lower than those of healthy people, and the inter-density was higher than that of the HS group, but the significance was different between LHS and RHS groups. The intra-density changes in the RHS group were opposite to those in the LHS group. The correlation between mesoscale indicators and motor function differed between dominant and non-dominant hemisphere stroke.
UNASSIGNED: The changes in macroscale cortical network indicators were similar between the two patient groups, while those of the mesoscale indicators were different. The mesoscale brain network characteristics were affected by the severity of dysfunction to varying degrees in the LHS and RHS patients.
UNASSIGNED: To analyze hemispheric dominance differences in task-state motor network properties in subacute stroke by functional near-infrared spectroscopy (fNIRS).
UNASSIGNED: Patients with first ischemic stroke in the basal ganglia within 1-3 months after onset and age- and sex-matched right-handed healthy subjects (HS) were enrolled. fNIRS with 29 channels was used to detect the oxyhemoglobin concentration changes when performing the hand grasping task. Activation patterns of motor cortex and two macroscale and two mesoscale brain network indicators based on graph theory were compared between dominant and non-dominant hemisphere stroke.
UNASSIGNED: We enrolled 17 subjects in each of left hemisphere stroke (LHS), right hemisphere stroke (RHS), and HS groups. Both patient groups showed bilateral activation. The average weighted clustering coefficient and global efficiency of patients were lower than those of healthy people, and the inter-density was higher than that of the HS group, but the significance was different between LHS and RHS groups. The intra-density changes in the RHS group were opposite to those in the LHS group. The correlation between mesoscale indicators and motor function differed between dominant and non-dominant hemisphere stroke.
UNASSIGNED: The changes in macroscale cortical network indicators were similar between the two patient groups, while those of the mesoscale indicators were different. The mesoscale brain network characteristics were affected by the severity of dysfunction to varying degrees in the LHS and RHS patients.
摘要：
■中风后大脑网络发生了重组。一些研究比较了显性和非显性半球中风之间皮质和皮质下区域的激活或功能连接（FC）的特征。
■通过功能近红外光谱（fNIRS）分析亚急性中风中任务状态运动网络特性的半球优势差异。
■在发病后1-3个月内首次发生基底节缺血性卒中的患者以及年龄和性别匹配的右手健康受试者（HS）。使用具有29个通道的fNIRS来检测执行手抓任务时的氧合血红蛋白浓度变化。在显性和非显性半球中风之间，比较了运动皮层的激活模式以及基于图论的两个宏观和两个中尺度脑网络指标。
■我们在左半球中风（LHS）中招募了17名受试者，右半球中风（RHS），和HS组。两组患者均显示双侧激活。患者的平均加权聚类系数和整体效率均低于健康人,间密度高于HS组，但LHS和RHS组之间的显著性不同。RHS组的密度内变化与LHS组相反。中尺度指标与运动功能之间的相关性在显性和非显性半球中风之间存在差异。
■两组患者的宏观皮层网络指标变化相似，而中尺度指标不同。LHS和RHS患者的中尺度脑网络特征在不同程度上受到功能障碍严重程度的影响。
■通过功能近红外光谱（fNIRS）分析亚急性中风中任务状态运动网络特性的半球优势差异。
■在发病后1-3个月内首次发生基底节缺血性卒中的患者以及年龄和性别匹配的右手健康受试者（HS）。使用具有29个通道的fNIRS来检测执行手抓任务时的氧合血红蛋白浓度变化。在显性和非显性半球中风之间，比较了运动皮层的激活模式以及基于图论的两个宏观和两个中尺度脑网络指标。
■我们在左半球中风（LHS）中招募了17名受试者，右半球中风（RHS），和HS组。两组患者均显示双侧激活。患者的平均加权聚类系数和整体效率均低于健康人,间密度高于HS组，但LHS和RHS组之间的显著性不同。RHS组的密度内变化与LHS组相反。中尺度指标与运动功能之间的相关性在显性和非显性半球中风之间存在差异。
■两组患者的宏观皮层网络指标变化相似，而中尺度指标不同。LHS和RHS患者的中尺度脑网络特征在不同程度上受到功能障碍严重程度的影响。
