PDF(Pubmed)
Abstract：
Human intestinal spirochetosis (HIS) is a condition where spirochetes, a group of spiral-shaped bacteria, attach to the apical membrane of the human colorectal epithelium. Although most findings of HIS are simply incidental discoveries found during screening colonoscopies, the ability to mimic the presentation of inflammatory bowel diseases should prompt consideration of this condition as part of a working differential diagnosis. Herein, we present the case of a 57-year-old bisexual, African American male with a medical history of Human Immunodeficiency Virus (HIV) on antiretroviral therapy (ART) with an undetectable viral load that presented for an elective, outpatient colonoscopy after experiencing four months of intermittent bloating and hematochezia. Histologic examination of colonic biopsies confirmed a diagnosis of HIS. The nonspecific clinical presentation in the setting of well-controlled HIV makes HIS a formidable diagnostic challenge that requires increased awareness.
摘要：
人类肠道螺旋体病（HIS）是一种螺旋体，一组螺旋形细菌，附着在人结肠直肠上皮的顶端膜上。尽管HIS的大多数发现只是在结肠镜检查中发现的偶然发现，模拟炎症性肠病表现的能力应促使将这种情况作为有效鉴别诊断的一部分加以考虑.在这里，我们介绍了一个57岁的双性恋者的案例，具有抗逆转录病毒疗法（ART）的人类免疫缺陷病毒（HIV）病史的非裔美国男性，病毒载量无法检测到，门诊结肠镜检查后经历四个月的间歇性腹胀和便血。结肠活检的组织学检查证实了HIS的诊断。在良好控制的HIV环境中的非特异性临床表现使HIS成为一个巨大的诊断挑战，需要提高意识。
