%0 Case Reports %T Human Intestinal Spirochetosis: A Rare Case of Intermittent Bloating and Hematochezia. %A Pérez Moux RL %A Mude P %A Doshi S %A Madwani K %A Barrett A %A Yap JEL %J Cureus %V 14 %N 6 %D Jun 2022 %M 35812607 暂无%R 10.7759/cureus.25756 %X Human intestinal spirochetosis (HIS) is a condition where spirochetes, a group of spiral-shaped bacteria, attach to the apical membrane of the human colorectal epithelium. Although most findings of HIS are simply incidental discoveries found during screening colonoscopies, the ability to mimic the presentation of inflammatory bowel diseases should prompt consideration of this condition as part of a working differential diagnosis. Herein, we present the case of a 57-year-old bisexual, African American male with a medical history of Human Immunodeficiency Virus (HIV) on antiretroviral therapy (ART) with an undetectable viral load that presented for an elective, outpatient colonoscopy after experiencing four months of intermittent bloating and hematochezia. Histologic examination of colonic biopsies confirmed a diagnosis of HIS. The nonspecific clinical presentation in the setting of well-controlled HIV makes HIS a formidable diagnostic challenge that requires increased awareness.