Abstract：
This clinical prospective randomized controlled study aimed to investigate the differences between Radial (RFFF) and Ulnar (UFFF) Forearm Free Flap in terms of success, performance, and donor site morbidity. Thirty patients with reconstruction of the head and neck region were included. For the first time, this study assessed flap-perfusion characteristics, donor-site-wound-healing dynamics and hand perfusion using hyperspectral imaging. Further, subjective (Likert-scale, DASH-score) and objective (grip/pinch-strength) parameters of donor site morbidity were analysed. Postoperative follow-up was performed until 6 months after index surgery. With 100% of patients, RFFF and UFFF were equally successful. Compared to surrounding reference, UFFF revealed significant lower tissue oxygenation saturation (StO2) than RFFF. Compared with UFFF, blood flow in both the thenar and hypothenar region were significantly reduced 6 months following RFFF transfer. After four weeks, 27% more patients demonstrated impaired wound healing following RFFF transfer. After 6 months, epithelial-surface continuity was restored in all patients of both groups. After 6 months, overall rates of both subjective and objective donor site morbidity were comparable between RFFF and UFFF. RFFF and UFFF both demonstrate similar success rates and HSI-perfusion dynamics following transfer. After 4 weeks, wound-healing disorder appeared significantly more often in RFFF than in UFFF; however, they became equal after 6 months. RFFF and UFFF can be considered as mutual alternatives.
摘要：
这项临床前瞻性随机对照研究旨在研究桡骨（RFFF）和尺骨（UFFF）前臂游离皮瓣在成功方面的差异，性能，和供体部位发病率。包括30例头颈部重建患者。第一次,这项研究评估了皮瓣灌注特征，使用高光谱成像的供体部位伤口愈合动力学和手灌注。Further,主观(李克特量表，DASH评分）和供体部位发病率的客观（握力/捏力）参数进行了分析。术后随访至索引手术后6个月。100%的患者，RFFF和UFFF同样成功。与周围的参考相比，UFFF显示组织氧合饱和度（StO2）明显低于RFFF。与UFFF相比,RFFF转移后6个月，鱼际和鱼际区域的血流量均显着减少。四周后,27％以上的患者在RFFF转移后表现出受损的伤口愈合。六个月后,两组患者的上皮表面连续性均恢复.六个月后,RFFF和UFFF的主观和客观供体部位的总体发病率相当.RFFF和UFFF均显示出相似的成功率和转移后的HSI灌注动力学。4周后,伤口愈合障碍在RFFF中的出现频率明显高于UFFF;然而，他们在6个月后变得平等。RFFF和UFFF可以被视为相互替代。
