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Abstract：
To evaluate the clinical profile and screening guidelines of retinopathy of prematurity (ROP) in an urban level III neonatal intensive care unit (NICU).
: Infants with ≤2000-gm birth weight or <34 weeks gestational age were prospectively screened for ROP in an urban level III NICU between January 2018 and December 2020, based on national screening guidelines. Standard guidelines were used for ROP classification and treatment.
In total, 211 infants completed screening; 46 (21.8%) infants developed ROP and 13 (6.2%) had type 1 (laser treatable) ROP. Of the 46 infants with ROP, 44 (95.65%) had zone 2 and two (4.34%) had zone 1 disease. In the 102 infants with ≤1500-gm birth weight, the incidence of ROP and type 1 ROP were 41.18% and 11.76%, respectively. Out of the 109 infants with >1500-gm birth weight, four (3.67%) developed ROP and one (0.91%) infant (an outborn) required treatment.
The majority of infants developing ROP in a level III urban NICU had ≤1500-gm birth weight. Zone 1 ROP was uncommon. Incidence of ROP in heavier infants (>1500-gm birth weight) was low, and treatment was required in a rare instance. In an urban NICU, the burden of ROP screening and treatments shifts to small and low-birth-weight infants.
: Infants with ≤2000-gm birth weight or <34 weeks gestational age were prospectively screened for ROP in an urban level III NICU between January 2018 and December 2020, based on national screening guidelines. Standard guidelines were used for ROP classification and treatment.
In total, 211 infants completed screening; 46 (21.8%) infants developed ROP and 13 (6.2%) had type 1 (laser treatable) ROP. Of the 46 infants with ROP, 44 (95.65%) had zone 2 and two (4.34%) had zone 1 disease. In the 102 infants with ≤1500-gm birth weight, the incidence of ROP and type 1 ROP were 41.18% and 11.76%, respectively. Out of the 109 infants with >1500-gm birth weight, four (3.67%) developed ROP and one (0.91%) infant (an outborn) required treatment.
The majority of infants developing ROP in a level III urban NICU had ≤1500-gm birth weight. Zone 1 ROP was uncommon. Incidence of ROP in heavier infants (>1500-gm birth weight) was low, and treatment was required in a rare instance. In an urban NICU, the burden of ROP screening and treatments shifts to small and low-birth-weight infants.
摘要：
评估城市III级新生儿重症监护病房（NICU）早产儿视网膜病变（ROP）的临床特征和筛查指南。
：根据国家筛查指南，2018年1月至2020年12月，在城市III级NICU中，对出生体重≤2000克或胎龄<34周的婴儿进行了ROP前瞻性筛查。标准指南用于ROP分类和治疗。
总共，211名婴儿完成筛查；46名（21.8％）婴儿发生ROP，13名（6.2％）患有1型（可激光治疗）ROP。在46名患有ROP的婴儿中，44例(95.65%)患有2区疾病，2例(4.34%)患有1区疾病。在102名出生体重≤1500克的婴儿中，ROP和1型ROP的发生率分别为41.18%和11.76%,分别。在109名出生体重>1500克的婴儿中，4名（3.67％）发生ROP，1名（0.91％）婴儿（外胎）需要治疗。
在III级城市NICU中，大多数发生ROP的婴儿出生体重≤1500克。1区ROP并不常见。重婴儿（>1500克出生体重）的ROP发生率较低，在极少数情况下需要治疗。在城市NICU，ROP筛查和治疗的负担转移到小体重儿和低出生体重儿身上.
：根据国家筛查指南，2018年1月至2020年12月，在城市III级NICU中，对出生体重≤2000克或胎龄<34周的婴儿进行了ROP前瞻性筛查。标准指南用于ROP分类和治疗。
总共，211名婴儿完成筛查；46名（21.8％）婴儿发生ROP，13名（6.2％）患有1型（可激光治疗）ROP。在46名患有ROP的婴儿中，44例(95.65%)患有2区疾病，2例(4.34%)患有1区疾病。在102名出生体重≤1500克的婴儿中，ROP和1型ROP的发生率分别为41.18%和11.76%,分别。在109名出生体重>1500克的婴儿中，4名（3.67％）发生ROP，1名（0.91％）婴儿（外胎）需要治疗。
在III级城市NICU中，大多数发生ROP的婴儿出生体重≤1500克。1区ROP并不常见。重婴儿（>1500克出生体重）的ROP发生率较低，在极少数情况下需要治疗。在城市NICU，ROP筛查和治疗的负担转移到小体重儿和低出生体重儿身上.
