Abstract：
OBJECTIVE: The red complex includes Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia, which are recognized as the most important pathogens and are the indicators of infection in chronic periodontal disease. This study was to assess the levels of red complex bacteria in chronic periodontitis patients following treatment with probiotic mouthwash.
METHODS: Twenty chronic periodontitis patients with ages ranging from 18 to 55 years were recruited for the study. The control group was given placebo mouthwash and the study group was given probiotic mouthwash. After clinical monitoring and scaling and root planing, the collected plaque samples at baseline and 14th day were transferred for microbiological analysis by transport media for Conventional Multiplex Polymerase Chain Reaction.
RESULTS: On the 14th day, all the clinical parameters were significantly reduced in the study group with gingival index (p = 0.003 HS) and plaque index (p = 0.001 VHS). In the study group, there was significant bacterial cell reduction with T. denticola (p = 0.041 S) and T. forsythia (p = 0.037 S).
CONCLUSIONS: In patients with chronic periodontitis, treatment with probiotic mouthwash significantly reduces the levels of red complex bacteria.
CONCLUSIONS: The use of probiotic mouthwash could be a useful adjunct to scaling and root planing in chronic periodontitis.
METHODS: Twenty chronic periodontitis patients with ages ranging from 18 to 55 years were recruited for the study. The control group was given placebo mouthwash and the study group was given probiotic mouthwash. After clinical monitoring and scaling and root planing, the collected plaque samples at baseline and 14th day were transferred for microbiological analysis by transport media for Conventional Multiplex Polymerase Chain Reaction.
RESULTS: On the 14th day, all the clinical parameters were significantly reduced in the study group with gingival index (p = 0.003 HS) and plaque index (p = 0.001 VHS). In the study group, there was significant bacterial cell reduction with T. denticola (p = 0.041 S) and T. forsythia (p = 0.037 S).
CONCLUSIONS: In patients with chronic periodontitis, treatment with probiotic mouthwash significantly reduces the levels of red complex bacteria.
CONCLUSIONS: The use of probiotic mouthwash could be a useful adjunct to scaling and root planing in chronic periodontitis.
摘要：
目的：红色复合体包括牙龈卟啉单胞菌，Denticola密螺旋体,还有连翘坦纳菌,被认为是最重要的病原体，是慢性牙周病感染的指标。这项研究旨在评估益生菌漱口水治疗后慢性牙周炎患者中红色复合细菌的水平。
方法：招募20名年龄在18至55岁之间的慢性牙周炎患者进行研究。对照组给予安慰剂漱口水,研究组给予益生菌漱口水。在临床监测、刮削和根部平整后，将基线和第14天收集的斑块样本转移至常规多重聚合酶链反应的转运介质进行微生物学分析.
结果：第14天，在牙龈指数(p=0.003HS)和菌斑指数(p=0.001VHS)的研究组中,所有临床参数均显著降低.在研究小组中,Denticola（p=0.041S）和连翘（p=0.037S）的细菌细胞显着减少。
结论：慢性牙周炎患者，用益生菌漱口水治疗可显着降低红色复合细菌的水平。
结论：益生菌漱口水的使用可能是慢性牙周炎中牙垢和牙根平整的有用辅助手段。
方法：招募20名年龄在18至55岁之间的慢性牙周炎患者进行研究。对照组给予安慰剂漱口水,研究组给予益生菌漱口水。在临床监测、刮削和根部平整后，将基线和第14天收集的斑块样本转移至常规多重聚合酶链反应的转运介质进行微生物学分析.
结果：第14天，在牙龈指数(p=0.003HS)和菌斑指数(p=0.001VHS)的研究组中,所有临床参数均显著降低.在研究小组中,Denticola（p=0.041S）和连翘（p=0.037S）的细菌细胞显着减少。
结论：慢性牙周炎患者，用益生菌漱口水治疗可显着降低红色复合细菌的水平。
结论：益生菌漱口水的使用可能是慢性牙周炎中牙垢和牙根平整的有用辅助手段。
