Abstract：
BACKGROUND: With the younger onset age of female lower genital tract diseases, there are increasing demands for protecting organ and tissue structures to preserve fertility and, therefore, effective fertility-sparing treatments that cause minimal normal tissue damage and less adverse reactions are urgently needed.
OBJECTIVE: This study is aimed at reviewing information and achieving consensus on recommendations on the clinical applications of aminolevulinic acid-based photodynamic therapy (ALA-PDT) in female lower genital tract diseases.
METHODS: Members of the expert panel held online and in-person meetings to discuss and revise drafts created by the steering committee based on the literature review and the clinical experiences of the expert panel. Opinions of the experts were transcribed and discussed in detail to ensure that the consensus statement best reflects the current advances in the field and the experts\' view.
RESULTS: After numerous rounds of meetings, experts unanimously agreed on the importance of ALA-PDT in the treatment of cervical squamous intraepithelial lesions (SIL), vaginal SIL, vulvar SIL, vulvar lichen sclerosus (VLS), and condyloma acuminatumon (CA). Experts also reached consensus on the recommended treatment regimen and treatment methods.
CONCLUSIONS: This consensus aimed to provide practical basis and guidance for the clinical applications of ALA-PDT in female lower genital tract diseases in China. Of note, this is the only expert consensus prepared by board-certified specialists in gynecology and obstetrics in China. More evidence-based clinical studies should be made to update and expand the current recommendations.
OBJECTIVE: This study is aimed at reviewing information and achieving consensus on recommendations on the clinical applications of aminolevulinic acid-based photodynamic therapy (ALA-PDT) in female lower genital tract diseases.
METHODS: Members of the expert panel held online and in-person meetings to discuss and revise drafts created by the steering committee based on the literature review and the clinical experiences of the expert panel. Opinions of the experts were transcribed and discussed in detail to ensure that the consensus statement best reflects the current advances in the field and the experts\' view.
RESULTS: After numerous rounds of meetings, experts unanimously agreed on the importance of ALA-PDT in the treatment of cervical squamous intraepithelial lesions (SIL), vaginal SIL, vulvar SIL, vulvar lichen sclerosus (VLS), and condyloma acuminatumon (CA). Experts also reached consensus on the recommended treatment regimen and treatment methods.
CONCLUSIONS: This consensus aimed to provide practical basis and guidance for the clinical applications of ALA-PDT in female lower genital tract diseases in China. Of note, this is the only expert consensus prepared by board-certified specialists in gynecology and obstetrics in China. More evidence-based clinical studies should be made to update and expand the current recommendations.
摘要：
背景：随着女性下生殖道疾病的发病年龄越来越小，保护器官和组织结构以保持生育能力的需求越来越高，因此,目前迫切需要有效的保留生育力的治疗,使正常组织损伤最小,不良反应较少.
目的：本研究旨在对基于氨基酮戊酸的光动力疗法（ALA-PDT）在女性下生殖道疾病中的临床应用进行信息审查并达成共识。
方法：专家小组成员举行在线和面对面会议，讨论和修改指导委员会根据文献综述和专家小组的临床经验创建的草案。对专家的意见进行了详细的转录和讨论，以确保共识声明最能反映该领域的当前进展和专家的观点。
结果：经过多轮会议，专家一致认为ALA-PDT在宫颈鳞状上皮内病变（SIL）治疗中的重要性，阴道SIL,外阴SIL,外阴硬化性苔藓（VLS），和尖锐湿疣（CA）。专家还就推荐的治疗方案和治疗方法达成共识。
结论：本共识旨在为ALA-PDT在我国女性下生殖道疾病中的临床应用提供实践依据和指导。值得注意的是，这是中国妇产科委员会认证专家编写的唯一专家共识。应进行更多基于证据的临床研究以更新和扩展当前的建议。
目的：本研究旨在对基于氨基酮戊酸的光动力疗法（ALA-PDT）在女性下生殖道疾病中的临床应用进行信息审查并达成共识。
方法：专家小组成员举行在线和面对面会议，讨论和修改指导委员会根据文献综述和专家小组的临床经验创建的草案。对专家的意见进行了详细的转录和讨论，以确保共识声明最能反映该领域的当前进展和专家的观点。
结果：经过多轮会议，专家一致认为ALA-PDT在宫颈鳞状上皮内病变（SIL）治疗中的重要性，阴道SIL,外阴SIL,外阴硬化性苔藓（VLS），和尖锐湿疣（CA）。专家还就推荐的治疗方案和治疗方法达成共识。
结论：本共识旨在为ALA-PDT在我国女性下生殖道疾病中的临床应用提供实践依据和指导。值得注意的是，这是中国妇产科委员会认证专家编写的唯一专家共识。应进行更多基于证据的临床研究以更新和扩展当前的建议。
