Abstract：
Paraneoplastic syndrome is a group of clinical symptoms that occur in the state of systemic malignant tumors. Paraneoplastic syndrome of the nervous system can affect any part of the central and peripheral nervous system and may also affect the eyes. In neuroophthalmology, paraneoplastic syndrome has a variety of manifestations that can affect both the afferent and efferent visual systems. The afferent system may involve the optic nerve, retina and uvea; the efferent system may involve eye movement, neuromuscular joints or involuntary eye movements and pupil abnormalities and may also have other neurological symptoms outside the visual system. This article discusses the clinical manifestations, pathological mechanisms, detection methods and treatment methods of paraneoplastic syndrome in neuroophthalmology. The performance of paraneoplastic syndrome is diverse, the diagnosis is difficult, and the treatment should be considered systematically. Differential diagnosis, optimal evaluation and management of these manifestations is not only the key to treatment but also a challenge.
摘要：
副肿瘤综合征是在全身恶性肿瘤状态下发生的一组临床症状。神经系统的副肿瘤综合征可以影响中枢和周围神经系统的任何部分，也可能影响眼睛。在神经眼科，副肿瘤综合征有多种表现，可影响传入和传出视觉系统。传入系统可能涉及视神经，视网膜和葡萄膜；传出系统可能涉及眼球运动，神经肌肉关节或不自主的眼球运动和瞳孔异常，也可能有视觉系统外的其他神经系统症状。本文讨论了临床表现，病理机制，神经眼科副肿瘤综合征的检测方法和治疗方法。副肿瘤综合征的表现多种多样，诊断是困难的，应该系统地考虑治疗。鉴别诊断,这些表现的最佳评估和管理不仅是治疗的关键，也是一个挑战。
