Abstract:
This review examines findings of musculoskeletal neoplasms whose equivocal imaging and/or histopathologic features make it difficult to determine if they will show aggressive behavior. We include both intermediate tumors as defined by the World Health Organization (WHO), and a single low-grade malignancy, low-grade central osteosarcoma, which mimics a benign lesion on imaging and histology. Intermediate tumors are a broad category and are subdivided into tumors that have risk of local recurrence only, and ones that have a risk of distant limb and pulmonary metastases. Difficult intermediate musculoskeletal lesions include atypical cartilaginous tumor/grade 1 chondrosarcoma, atypical lipomatous tumor/grade 1 liposarcoma, and solitary fibrous tumor. We review diagnostic criteria, differential diagnosis, and recommendations for surveillance.
摘要:
这篇综述研究了肌肉骨骼肿瘤的发现,这些肿瘤的影像学和/或组织病理学特征令人难以确定它们是否会表现出攻击行为。我们包括世界卫生组织(WHO)定义的中间肿瘤,和单一的低度恶性肿瘤,低级中央骨肉瘤,在影像学和组织学上模仿良性病变。中间肿瘤是一个广泛的类别,细分为仅有局部复发风险的肿瘤,和那些有远处肢体和肺转移风险的。困难的中间肌肉骨骼病变包括非典型软骨肿瘤/1级软骨肉瘤,非典型脂肪瘤瘤/1级脂肪肉瘤,和孤立性纤维瘤。我们回顾诊断标准,鉴别诊断,和监督建议。