关键词： CBLL, chilblain-like lesion COVID toes COVID-19 EBV, Epstein-Barr virus Epstein-Barr virus (EBV) IFN, interferon Ig, immunoglobulin RT-PCR, reverse transcriptase polymerase chain reaction acral lesions acro-ischemia chilblain-like lesions (CBLL) chilblains coronavirus cutaneous vasculitis factor V Leiden humoral immunity infection interferon (IFN) lipoprotein A pandemic pernio postacute sequelae of COVID-19 (PASC) pseudo-chilblains skin of color vaccine virus CBLL, chilblain-like lesion COVID toes COVID-19 EBV, Epstein-Barr virus Epstein-Barr virus (EBV) IFN, interferon Ig, immunoglobulin RT-PCR, reverse transcriptase polymerase chain reaction acral lesions acro-ischemia chilblain-like lesions (CBLL) chilblains coronavirus cutaneous vasculitis factor V Leiden humoral immunity infection interferon (IFN) lipoprotein A pandemic pernio postacute sequelae of COVID-19 (PASC) pseudo-chilblains skin of color vaccine virus

来  源：   DOI：10.1016/j.jdin.2022.06.012   PDF(Pubmed)

Abstract：
\"COVID toes\" is the colloquial name of chilblain-like lesions thought to be a sequela of COVID-19 infection. Over two years and approximately 300 publications later, this association remains controversial. Here, we summarize key clinical, serological, biological, histological, and immunological evidence that supports and rejects this relationship and discuss alternate theories underlying the pathogenesis of chilblain-like lesions.
摘要：
“COVID脚趾”是冻疮样病变的俗称，被认为是COVID-19感染的后遗症。两年多来，大约300种出版物，这个协会仍然存在争议。这里,我们总结了关键的临床，血清学,生物，组织学,以及支持和拒绝这种关系的免疫学证据，并讨论了冻疮样病变发病机理的替代理论。
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