Abstract：
Herein, a molecularly imprinted surface-enhanced Raman spectroscopy (SERS) sensor was developed for the selective capture and sensitive detection of tryptamine in foods. The SERS sensor exploited silver nanoparticle-decorated TiO2 (TiO2@Ag) substrates for Raman signal enhancement via synergistic effect of electromagnetic enhancement and photoinduced charge-transfer, whilst surface functionalization with the molecularly imprinted polymer ensured selective tryptamine capture. The SERS spectrum of tryptamine on the sensor closely matched that predicted by density functional simulations. The SERS intensity for tryptamine on the developed TiO2@Ag@MIP sensor increased linearly with the logarithm of the tryptamine concentration over the range of 10-6-10-2 mol L-1, with a LOD of 4.85 × 10-7 mol L-1. Tryptamine was detected in a spiked white vinegar sample, and its recoveries were in the range of 92.00%-111.40%. The SERS sensor could be used for the detection of tryptamine in actual samples.
摘要：
在这里，开发了分子印迹表面增强拉曼光谱（SERS）传感器，用于食品中色胺的选择性捕获和灵敏检测。SERS传感器利用银纳米粒子修饰的TiO2（TiO2@Ag）衬底通过电磁增强和光诱导电荷转移的协同作用增强拉曼信号，而分子印迹聚合物的表面官能化确保了色胺的选择性捕获。传感器上色胺的SERS光谱与密度泛函模拟预测的光谱紧密匹配。在10-6-10-2molL-1范围内，开发的TiO2@Ag@MIP传感器上色胺的SERS强度随色胺浓度的对数线性增加，LOD为4.85×10-7molL-1。在加标的白醋样品中检测到色胺，回收率在92.00%-111.40%之间。SERS传感器可用于实际样品中色胺的检测。
