Abstract:
The current high detection rate of adrenal tumors (4-10% of general population) is attributable to a widespread use of variety of imaging studies, especially a computed tomography. Most of them represent clinically silent and biologically indolent incidentalomas, but some adrenal tumors may pose a significant clinical challenge. Thus, in every patient with an adrenal tumor, a decision on further management is made after careful hormonal and radiological evaluation. All hormonally active tumors and those with radiological features suggesting malignancy are qualified for surgery. Approximately 80% of adrenal tumors are adrenocortical adenomas, hypertrophy, or nodular adrenocortical hyperplasia. Other histopathological diagnoses include pheochromocytoma, adrenocortical carcinoma, metastases, mesenchymal tumors, lymphomas, cysts, and ganglioneuromas. Adrenal tumors are more commonly diagnosed and better studied in elderly patients. In younger patients, under 40 years old, focal adrenal lesions are relatively rare, and histological distribution of diagnoses differs from that in elderly individuals. Younger patients are more likely to display endocrine symptoms, which raise the suspicion of an adrenal mass. In the current study, we present a case series of seven adrenal tumors occurring in young patients. The cases presented below, along with the literature review, demonstrate that the diagnosis and treatment of adrenal tumors are crucial due to endocrinopathy-derived complications and a potential risk of malignancy.
摘要:
目前肾上腺肿瘤的高检出率(占普通人群的4-10%)归因于各种影像学研究的广泛使用,尤其是计算机断层扫描.它们中的大多数代表临床上无症状和生物惰性偶发瘤,但是一些肾上腺肿瘤可能构成重大的临床挑战。因此,每个肾上腺肿瘤患者,经过仔细的激素和放射学评估后,决定进一步管理。所有激素活性肿瘤和具有放射学特征提示恶性肿瘤的肿瘤均可进行手术。大约80%的肾上腺肿瘤是肾上腺皮质腺瘤,肥大,或结节性肾上腺皮质增生。其他组织病理学诊断包括嗜铬细胞瘤,肾上腺皮质癌,转移,间充质肿瘤,淋巴瘤,囊肿,和神经节神经瘤.肾上腺肿瘤更常见的诊断和更好的研究在老年患者。在年轻患者中,40岁以下,局灶性肾上腺病变相对罕见,诊断的组织学分布与老年人不同。年轻患者更容易出现内分泌症状,引起肾上腺肿块的怀疑.在目前的研究中,我们介绍了一个病例系列,其中7例发生在年轻患者中的肾上腺肿瘤。下面介绍的案例,随着文献综述,证明肾上腺肿瘤的诊断和治疗是至关重要的,因为内分泌病源性并发症和恶性肿瘤的潜在风险。