Abstract：
In the last decades, the interest in seaweed has significantly increased. Bioactive compounds from seaweed\'s currently receive major attention from pharmaceutical companies as they express several interesting biological activities which are beneficial for humans. The structural diversity of seaweed metabolites provides diverse biological activities which are expressed through diverse mechanisms of actions. This review mainly focuses on the antiviral activity of seaweed\'s extracts, highlighting the mechanisms of actions of some seaweed molecules against infection caused by different types of enveloped viruses: influenza, Lentivirus (HIV-1), Herpes viruses, and coronaviruses. Seaweed metabolites with antiviral properties can act trough different pathways by increasing the host\'s defense system or through targeting and blocking virus replication before it enters host cells. Several studies have already established the large antiviral spectrum of seaweed\'s bioactive compounds. Throughout this review, antiviral mechanisms and medical applications of seaweed\'s bioactive compounds are analyzed, suggesting seaweed\'s potential source of antiviral compounds for the formulation of novel and natural antiviral drugs.
摘要：
在过去的几十年里，对海藻的兴趣显著增加。来自海藻的生物活性化合物目前受到制药公司的主要关注，因为它们表现出几种对人类有益的有趣的生物活性。海藻代谢物的结构多样性提供了通过不同作用机制表达的不同生物活性。这篇综述主要集中在海藻提取物的抗病毒活性。强调一些海藻分子对不同类型的包膜病毒引起的感染的作用机制：流感，慢病毒（HIV-1），疱疹病毒,和冠状病毒。具有抗病毒特性的海藻代谢物可以通过不同的途径起作用，通过增加宿主的防御系统或通过在病毒进入宿主细胞之前靶向和阻断病毒复制。一些研究已经建立了海藻生物活性化合物的大抗病毒谱。在整个审查过程中，分析了海藻生物活性化合物的抗病毒机制和医学应用，建议海藻的抗病毒化合物的潜在来源，用于配制新型和天然抗病毒药物。
