OBJECTIVE: To address the role of physical, chemical, mechanical, and biological characteristics in order to determine the critical parameters to improve biological responses and the long-term effectiveness of dental implant surfaces.
METHODS: Web of Science, MEDLINE and Lilacs databases were searched for the last 30 years in English, Spanish and Portuguese idioms.
RESULTS: Chemical composition, wettability, roughness, and topography of dental implant surfaces have all been linked to biological regulation in cell interactions, osseointegration, bone tissue and peri-implant mucosa preservation.
CONCLUSIONS: Techniques involving subtractive and additive methods, especially those involving laser treatment or embedding of bioactive nanoparticles, have demonstrated promising results. However, the literature is heterogeneous regarding study design and methodology, which limits comparisons between studies and the definition of the critical determinants of optimal cell response.
目的:为了解决身体,化学,机械,和生物学特性,以确定改善生物反应和牙种植体表面长期有效性的关键参数。
方法:WebofScience,在过去的30年中,搜索了MEDLINE和Lilacs数据库,西班牙语和葡萄牙语的成语。
结果:化学成分,润湿性,粗糙度,和牙种植体表面的形貌都与细胞相互作用中的生物调节有关,骨整合,骨组织和种植体周围粘膜保存。
结论:涉及减法和加法方法的技术,尤其是那些涉及激光治疗或生物活性纳米粒子的嵌入,已经证明了有希望的结果。然而,关于研究设计和方法论的文献是不同的,这限制了研究与最佳细胞反应的关键决定因素的定义之间的比较。