UNASSIGNED: a retrospective, observational study of all adult meningitis cases, managed at the National District Hospital (NDH) Bloemfontein, Free State Province, South Africa between January 2017 and December 2019.
UNASSIGNED: of the 236 case files reviewed, majority (93.2%; n=220) of the patients managed for meningitis were black, as well as males (55.5%; n = 131). Higher incidence was found between the ages 20 to 49 (81.7%). Of those who died, the majority (n = 14; 63.6%) were males, in the age group 40-49 (n = 7; 31.8%), had TB meningitis (n = 12; 54.5%), were HIV positive (n = 20; 90.9%), and had cell count <100 cells/mm3 (n = 10; 45.5%).
UNASSIGNED: our study suggests that combining information on patient demography, co-morbidities, clinical presentation, and examination findings can substantially contribute to raising clinical suspicion, leading to swift identification, diagnosis, and treatment of patients.
■回顾,所有成人脑膜炎病例的观察性研究,在国家地区医院(NDH)布隆方丹管理,自由州省,2017年1月至2019年12月之间的南非。
■在所审查的236份案卷中,大多数(93.2%;n=220)的脑膜炎患者是黑人,以及男性(55.5%;n=131)。在20至49岁之间发现较高的发病率(81.7%)。那些死去的人,大多数(n=14;63.6%)是男性,在40-49岁年龄组(n=7;31.8%),患有结核性脑膜炎(n=12;54.5%),HIV阳性(n=20;90.9%),并且细胞计数<100个细胞/mm3(n=10;45.5%)。
■我们的研究表明,结合患者人口统计信息,合并症,临床表现,和检查结果可以大大有助于提高临床怀疑,导致快速识别,诊断,以及对患者的治疗。