关键词: AS-OCT Brimonidine corneal stromal inflammation hypotonic maculopathy ocular hypotony

Mesh : Male Humans Aged Brimonidine Tartrate / therapeutic use Cornea Intraocular Pressure Conjunctivitis / diagnosis Retinal Diseases Macular Degeneration Ocular Hypertension Ophthalmic Solutions

来  源:   DOI:10.1080/09273948.2022.2087687

Abstract:
UNASSIGNED: Brimonidine is a commonly used drug for glaucoma treatment, which has been linked to ocular autoimmune disorders like uveitis and conjunctivitis. Corneal pathology under brimonidine is generally less common.
UNASSIGNED: Here, we report a 78 -year-old male patient suffering from immune corneal stromal inflammation with hypotony and resulting hypotonic maculopathy after 6 weeks after introduction of brimonidine treatment. Systemic work-up for system autoimmune and infectious diseases was negative. We discontinued brimonidine and administered topical prednisolone under which inflammatory corneal signs and intraocular pressure normalized. Chorioretinal folds persisted after 9 months.
UNASSIGNED: Our case report suggests monitoring patients under brimonidine for sterile corneal infiltration.
摘要:
溴莫尼定是治疗青光眼的常用药物,与眼自身免疫性疾病如葡萄膜炎和结膜炎有关。溴莫尼定下的角膜病理学通常不太常见。
这里,我们报道了1例78岁的男性患者,在接受溴莫尼定治疗6周后,出现了低眼压和低张性黄斑病变。系统自身免疫性和感染性疾病的系统性检查为阴性。我们停止了溴莫尼定,并局部使用泼尼松龙,在这种情况下,炎性角膜体征和眼内压恢复正常。脉络膜视网膜皱褶在9个月后持续存在。
我们的病例报告建议监测患者在溴莫尼定下的无菌角膜浸润。
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