{Reference Type}: Case Reports
{Title}: A Case of Sterile Corneal Stromal Infiltration with Hypotonic Maculopathy Under Brimonidine Treatment.
{Author}: Vidal Oliver L;Díaz Barrón A;López Montero A;Gil-Hernández I;Duch Samper AM;
{Journal}: Ocul Immunol Inflamm
{Volume}: 31
{Issue}: 8
{Year}: Oct 2023 16
{Factor}: 3.728
{DOI}: 10.1080/09273948.2022.2087687
{Abstract}: UNASSIGNED: Brimonidine is a commonly used drug for glaucoma treatment, which has been linked to ocular autoimmune disorders like uveitis and conjunctivitis. Corneal pathology under brimonidine is generally less common.
UNASSIGNED: Here, we report a 78 -year-old male patient suffering from immune corneal stromal inflammation with hypotony and resulting hypotonic maculopathy after 6 weeks after introduction of brimonidine treatment. Systemic work-up for system autoimmune and infectious diseases was negative. We discontinued brimonidine and administered topical prednisolone under which inflammatory corneal signs and intraocular pressure normalized. Chorioretinal folds persisted after 9 months.
UNASSIGNED: Our case report suggests monitoring patients under brimonidine for sterile corneal infiltration.