Abstract：
Vitiligo is an acquired chronic depigmentation disorder that can have a negative impact on the quality of life (QoL). This is especially true for patients with non-white skin. Only few studies have investigated the QoL of Asian patients with vitiligo. We aimed to investigate the QoL in Taiwanese vitiligo patients and identify the factors that influence their QoL. The cross-sectional study recruited 100 vitiligo patients and 100 controls with general skin diseases in the Department of Dermatology of Changhua Christian Hospital. Data were obtained using a structured questionnaire for demographic information and modified Skindex-21 instruments. The QoL was not significantly different between vitiligo patients and controls. Among the vitiligo patients, adults exhibited deteriorated emotional levels and total QoL as compared with non-adults. Married females reported greater levels of emotional disturbance than the unmarried ones. A higher educational level and shorter history of disease were associated with greater emotional impacts. The patients with a generalized type of vitiligo suffered more in total QoL. After multivariate adjustment, the young adult patients aged 20-39 were associated with poorer total QoL. It is suggested that vitiligo patients who are aged between 20 and 39, are married females, are highly educated, have a shorter disease history, and suffer from the generalized type of this disease demonstrate more deterioration in their life quality compared with other vitiligo patients. Care providers should tailor the psychological counseling and treatment accordingly.
摘要：
白癜风是一种获得性慢性色素脱失障碍，可对生活质量（QoL）产生负面影响。对于非白色皮肤的患者尤其如此。只有少数研究调查了亚洲白癜风患者的QoL。我们旨在调查台湾白癜风患者的QoL，并确定影响其QoL的因素。这项横断面研究招募了彰化基督教医院皮肤科的100名白癜风患者和100名普通皮肤病对照。数据是使用结构化的人口统计信息问卷和改良的Skindex-21工具获得的。白癜风患者和对照组之间的QoL没有显着差异。在白癜风患者中，与非成年人相比，成年人表现出情绪水平和总QoL恶化。已婚女性的情绪障碍程度高于未婚女性。较高的教育水平和较短的病史与较大的情感影响有关。泛发性白癜风患者的总生活质量更高。经过多变量调整后，年龄在20~39岁的年轻成年患者的总QoL较差.建议年龄在20至39岁之间的白癜风患者为已婚女性，受过高等教育，有较短的病史，与其他白癜风患者相比，患有这种疾病的广泛性类型显示出更多的生活质量恶化。护理提供者应相应地调整心理咨询和治疗。
