Abstract：
Two new isoflavones (1 and 2), as well as eight known ones were isolated from the roots of Sophora tonkinensis Gagnep. Compound 1 represents an unprecedented polymerization pattern constructed by isoflavone and cytisine. Their structures were elucidated by comprehensive spectroscopic data analysis, combined with ECD calculations. Compound 1 displayed significant anti-tobacco mosaic virus (TMV) activity compared with the positive control ningnanmycin. Moreover, compound 6 exhibited potent α-glucosidase inhibitory activity with IC50 value of 47.4 mg/L.
摘要：
两种新的异黄酮（1和2），从山豆根中分离出八种已知的山豆根。化合物1代表了由异黄酮和金雀花碱构建的前所未有的聚合模式。通过全面的光谱数据分析阐明了它们的结构，结合ECD计算。与阳性对照宁南霉素相比,化合物1显示出显著的抗烟草花叶病毒(TMV)活性。此外，化合物6显示出有效的α-葡萄糖苷酶抑制活性，IC50值为47.4mg/L。
