[Desmoid-type fibromatosis of the breast: about two cases and literature review].

[乳腺纤维样型纤维瘤病 ： 约 2 例并文献复习] 。

• 发表时间: 2022
• 来源期刊: Pan Afr Med J
• DOI: 10.11604/pamj.2022.41.184.28549
• PMID: 35655675
• 文章类型: Case Reports
• 作者列表: Laakom O,Bergaoui H,Hammouda SB,Khalfalli A,Njim L,Faleh R

关键词: Breast fibromatosis; adjuvant therapy; case report; imaging; margins

Mesh: Breast Neoplasms / diagnosis pathology therapy; Female; Fibroma / diagnosis therapy; Fibromatosis, Aggressive / diagnosis pathology therapy; Humans; Margins of Excision

Abstract

Breast fibromatosis is a benign breast tumor of mesenchymal origin, accounting for 0.2% of breast tumors. This study reports two cases of breast fibromatosis highlighting its diagnostic, morphological, therapeutic and evolutionary features. In both cases, this tumor clinically and radiologically mimicked a cancer. Diagnostic confirmation was based on histological examination. Breast fibromatosis was characterized by local progression and a tendency to recurrence, hence the role of surgical excision with free surgical margins in our patients. The role of locoregional treatments (radiotherapy and cryotherapy) and medical treatments, in particular anti-estrogen therapy, is not clearly defined. In conclusion, breast fibromatosis must be known as it mimicks breast cancer and is characterized by a very high recurrence rate, without ever developing metastases.

摘要

乳腺纤维瘤病是间质起源的良性乳腺肿瘤，占乳腺肿瘤的0.2%。本研究报告两例乳腺纤维瘤病突出其诊断，形态学,治疗和进化特征。在这两种情况下，这种肿瘤在临床和放射学上模仿癌症。诊断确认基于组织学检查。乳腺纤维瘤病的特点是局部进展和复发倾向，因此，在我们的患者中，具有自由手术切缘的手术切除的作用。局部治疗（放疗和冷冻治疗）和药物治疗的作用，特别是抗雌激素治疗，没有明确定义。总之,必须知道乳腺纤维瘤病，因为它模仿乳腺癌，具有非常高的复发率，没有发展转移。