关键词: Mondor disease Sildenafil citrate Venous thrombosis

来  源:   DOI:10.12701/jyms.2022.00220

Abstract:
Penile Mondor disease (MD) is a palpable, painful, subcutaneous induration caused by superficial dorsal penile vein thrombosis. We report a case of penile MD that was suspected to be related to prolonged oral sildenafil use. A 46-year-old man visited our emergency department with sustained penile pain and swelling that began 7 hours after sexual intercourse. He had used oral sildenafil intermittently for 11 years and engaged in sexual intercourse the previous night after taking sildenafil. Examination revealed no evidence of intercourse-related trauma to the genital area or an increase in penile skin temperature. However, penile swelling and tenderness over the protruding dorsal penile vein were noted. A color Doppler ultrasound examination was performed immediately, which showed hyperechoic thrombosis in the right superficial dorsal penile vein that was dilated, with soft tissue swelling and no detectable flow signal in the thrombotic lesion. The patient was diagnosed as having penile MD. The patient was treated conservatively. Some reports have indicated the involvement of sildenafil in thrombogenesis. Physicians should be aware that prolonged oral sildenafil use may be associated with penile MD.
摘要:
阴茎蒙多病(MD)是一种明显的,痛苦,阴茎背侧浅静脉血栓形成引起的皮下硬结。我们报告了一例阴茎MD,怀疑与长期口服西地那非有关。一名46岁的男子在性交后7小时出现持续的阴茎疼痛和肿胀,来到了我们的急诊科。他间歇性地使用口服西地那非11年,并在服用西地那非后的前一天晚上进行性交。检查未发现生殖器区域与性交有关的创伤或阴茎皮肤温度升高的证据。然而,注意到阴茎背部静脉突出的阴茎肿胀和压痛。立即进行彩色多普勒超声检查,显示右侧阴茎背侧浅静脉扩张的高回声血栓形成,软组织肿胀,血栓性病变中没有可检测到的血流信号。患者被诊断为患有阴茎MD。患者接受保守治疗。一些报道表明西地那非参与血栓形成。医生应该意识到,长期口服西地那非可能与阴茎MD有关。
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