PDF(Pubmed)
Abstract：
UNASSIGNED: Cue-induced craving is widely considered to be the most important risk factor for relapse during abstinence from methamphetamine (Meth). There is limited research regarding electroencephalography (EEG) microstates of Meth-dependent patients under exposure to drug-related cues. Our objective was to investigate whether EEG microstate temporal characteristics could capture neural correlates of cue-induced Meth craving in virtual reality (VR) environments.
UNASSIGNED: EEG recordings of 35 Meth-dependent patients and 30 healthy controls (HCs) were collected during eyes-open state and cue-induced state, respectively. Group differences and condition differences in temporal parameters of four microstate classes were compared.
UNASSIGNED: The results demonstrated the greater presence of microstate B in both Meth-dependent patients and HCs during the cue-induced condition, compared to resting state. In addition, for Meth-dependent patients, microstate C occurred significantly less frequently, along with a tendency of increased occurrence for class D during the cue-induced condition, compared to resting state. However, the change direction of class C and class D in HCs was completely opposite to that of Meth-dependent patients. The cue-induced condition also elicited different changes in transition probability between Meth-dependent patients and HCs.
UNASSIGNED: This study explored the features of EEG microstates in Meth-dependent patients during the cue-induced condition, which can improve our understanding of Meth addiction and contribute to the development of effective assessments and intervention tools.
UNASSIGNED: EEG recordings of 35 Meth-dependent patients and 30 healthy controls (HCs) were collected during eyes-open state and cue-induced state, respectively. Group differences and condition differences in temporal parameters of four microstate classes were compared.
UNASSIGNED: The results demonstrated the greater presence of microstate B in both Meth-dependent patients and HCs during the cue-induced condition, compared to resting state. In addition, for Meth-dependent patients, microstate C occurred significantly less frequently, along with a tendency of increased occurrence for class D during the cue-induced condition, compared to resting state. However, the change direction of class C and class D in HCs was completely opposite to that of Meth-dependent patients. The cue-induced condition also elicited different changes in transition probability between Meth-dependent patients and HCs.
UNASSIGNED: This study explored the features of EEG microstates in Meth-dependent patients during the cue-induced condition, which can improve our understanding of Meth addiction and contribute to the development of effective assessments and intervention tools.
摘要：
未经证实：提示引起的渴望被广泛认为是戒除甲基苯丙胺（Meth）期间复发的最重要风险因素。关于暴露于药物相关线索的Meth依赖患者的脑电图（EEG）微观状态的研究有限。我们的目的是研究EEG微观状态时间特征是否可以捕获虚拟现实（VR）环境中提示引起的Meth渴望的神经相关性。
UNASSIGNED：在睁眼状态和提示诱导状态下，收集了35例依赖药物的患者和30例健康对照（HCs）的EEG记录，分别。比较了四个微状态类别的时间参数的组差异和条件差异。
UNASSIGNED：结果表明，在提示诱发的情况下，在Meth依赖患者和HCs中，微状态B的存在更大，与静止状态相比。此外,对于依赖甲基的患者，微状态C的发生频率明显较低，随着D类在线索诱导条件下发生率增加的趋势，与静止状态相比。然而,HCs中C类和D类的变化方向与Meth依赖患者的变化方向完全相反。提示诱发的情况也引起了Meth依赖患者和HCs之间转移概率的不同变化。
UNASSIGNED：这项研究探索了在提示诱导条件下，Meth依赖患者的EEG微状态的特征，这可以提高我们对毒瘾的理解，并有助于开发有效的评估和干预工具。
UNASSIGNED：在睁眼状态和提示诱导状态下，收集了35例依赖药物的患者和30例健康对照（HCs）的EEG记录，分别。比较了四个微状态类别的时间参数的组差异和条件差异。
UNASSIGNED：结果表明，在提示诱发的情况下，在Meth依赖患者和HCs中，微状态B的存在更大，与静止状态相比。此外,对于依赖甲基的患者，微状态C的发生频率明显较低，随着D类在线索诱导条件下发生率增加的趋势，与静止状态相比。然而,HCs中C类和D类的变化方向与Meth依赖患者的变化方向完全相反。提示诱发的情况也引起了Meth依赖患者和HCs之间转移概率的不同变化。
UNASSIGNED：这项研究探索了在提示诱导条件下，Meth依赖患者的EEG微状态的特征，这可以提高我们对毒瘾的理解，并有助于开发有效的评估和干预工具。
