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Abstract：
Objective: Survey pediatricians and guardians of children with tic disorder on medication needs and choices. Methods: We designed a cross-sectional survey for pediatricians in mainland China, Hong Kong, Macao, and Taiwan, as well as for the guardians of patients with tic disorder from West China Second University Hospital. We collected and analyzed information on clinicians\' medical behavior and medication choices and on guardians\' knowledge of tic disorder, medical treatment behaviors, and medication choices and needs. Results: We collected responses from 242 physicians and 610 guardians. For patients with tic disorder and without comorbidities, the first-line drugs selected by physicians were tiapride (60.74%), clonidine (32.64%), haloperidol (25.62%), aripiprazole (16.53%), and sulpiride (12.4%). Physicians reported making medication choices by considerations such as clinical guidelines, clinical efficacy, a low incidence of adverse drug reactions, sufficient clinical research evidence, convenient dosage forms, and patient adherence. Guardians reported making medication choices by considerations such as a low incidence of adverse drug reactions, physician recommendations, clinical efficacy, dose, dosage forms, and the convenience and steadiness of obtaining the medication. However, guardians exhibited insufficient knowledge of tic disorder and treatment options. Conclusions: Physicians and patient guardians differ in their considerations when selecting medications, highlighting a gap in optimizing treatment.
摘要：
目的:调查儿童抽动障碍的儿科医生和监护人对药物治疗的需求和选择。方法：我们为中国大陆的儿科医生设计了一项横断面调查，香港,澳门,台湾,以及华西第二大学附属医院抽动障碍患者的监护人。我们收集并分析了临床医生的医疗行为和药物选择以及监护人对抽动障碍的知识，医疗行为，药物的选择和需求。结果：我们收集了242名医生和610名监护人的回复。对于有抽动障碍且没有合并症的患者，医生选择的一线药物是tiapride(60.74%)，可乐定（32.64%），氟哌啶醇(25.62%),阿立哌唑（16.53%），和舒必利(12.4%)。医生报告说，根据临床指南等考虑因素做出药物选择，临床疗效,药物不良反应发生率低，足够的临床研究证据，方便的剂型，和患者的依从性。监护人报告说，考虑到药物不良反应的低发生率等因素来选择药物。医生建议,临床疗效,剂量,剂型,以及获得药物的便利性和稳定性。然而,监护人对抽动障碍和治疗方案的知识不足。结论：医师和患者监护人在选择药物时的考虑因素不同，突出了优化治疗的差距。
