关键词: Cancer Dermoscopy Skin malignancies Skin metastases

Mesh : Biopsy Dermoscopy Humans Melanoma / pathology Skin / pathology Skin Neoplasms / pathology

来  源:   DOI:10.1053/j.seminoncol.2022.04.005

Abstract:
According to the literature, skin metastases affect 0.7%-10.4% of patients with malignant neoplasms of internal organs and may be 1 presentation of systemic spread of the cancer. Skin metastases may be the first sign of relapse after treatment and about 30% of cases of skin metastases are diagnosed before the diagnosis of internal organ cancer. Cutaneous metastases most often come from breast cancer and melanoma. They can present synchronous or metachronous. Adequate vigilance, combined with knowledge of the clinical picture and epidemiology, can contribute to accurate diagnosis and treatment. Clinically, skin metastases occur in the form of atypical solitary, painless nodules, or tumors. Lumps or infiltrating foci do not show clinical features that help in making a diagnosis. Skin changes are more accessible during physical examination, and it is easier to do a biopsy and provide histological assessment. Dermoscopy, a useful initial tool for the assessment of skin metastases, can lead to a rapid accurate diagnosis and treatment. Ultimately, the diagnosis of a metastatic malignancy is confirmed by histopathological examination.
摘要:
根据文献,皮肤转移影响内脏器官恶性肿瘤患者的0.7%-10.4%,可能是癌症全身扩散的表现。皮肤转移可能是治疗后复发的第一个迹象,大约30%的皮肤转移病例在诊断内脏器官癌之前就被诊断出来。皮肤转移最常来自乳腺癌和黑色素瘤。它们可以呈现同步或异时。足够的警惕,结合临床表现和流行病学的知识,有助于准确的诊断和治疗。临床上,皮肤转移以非典型单发的形式发生,无痛结节,或肿瘤。肿块或浸润灶不显示有助于诊断的临床特征。体格检查期间皮肤变化更容易接近,并且更容易进行活检和提供组织学评估。皮肤镜,评估皮肤转移的有用的初始工具,可以导致快速准确的诊断和治疗。最终,转移性恶性肿瘤的诊断通过组织病理学检查得到证实。
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