关键词: antibiotics bone pathology deficiency fistulae glucose-6-phosphate dehydrogenase jaws maxillae osteomyelitis sequestra treatment

Mesh : Female Humans Glucosephosphate Dehydrogenase Deficiency Maxilla Osteomyelitis / complications surgery Diabetes Mellitus Bone Diseases

来  源:   DOI:10.1111/scd.12729

Abstract:
OBJECTIVE: To report the case of chronic osteomyelitis of a maxilla in a woman with uncontrolled diabetes mellitus (DM), glucose-6-phosphate dehydrogenase (G6PD) deficiency and mental illness, in an attempt to clarify its pathogenesis and treatment.
RESULTS: A case of a woman with moderate G6PD deficiency (Class III) who developed bilateral and asynchronous chronic suppurative osteomyelitis (CSO) of her maxilla with extensive bone sequestra, fistulae and whose management was performed by local surgery for bony sequestra and fistulae removal; closure communication under 4 weeks antibiotic cover.
CONCLUSIONS: CSO of the jaw may be a complication of the G6PD deficiency and DM and its severity depends on patient\'s medical status.
摘要:
目的:报告患有未控制的糖尿病(DM)的女性上颌骨慢性骨髓炎的病例,葡萄糖-6-磷酸脱氢酶(G6PD)缺乏症和精神疾病,试图阐明其发病机制和治疗方法。
结果:一例患有中度G6PD缺乏症(III类)的妇女,其上颌骨发生双侧和非同步慢性化脓性骨髓炎(CSO),并伴有广泛的骨后遗症,瘘管,其管理通过局部手术进行骨隔离和瘘管清除;在4周抗生素覆盖下进行封闭通信。
结论:颌骨的CSO可能是G6PD缺乏症和DM的并发症,其严重程度取决于患者的医疗状况。
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