关键词: autopsy post-mortem pre-existing conditions sudden unexpected death unexplained

Mesh : Autopsy Cause of Death Child Female Humans Infant Male Retrospective Studies Specialization Sudden Infant Death / etiology pathology

来  源:   DOI:10.1177/10935266221099787

Abstract:
UNASSIGNED: To investigate the aetiologies of sudden unexpected death from natural causes in children aged 1-18 years by retrospective examination of autopsy records from a single centre.
UNASSIGNED: The post-mortem findings from 548 children (1996-2015) were examined. Details were entered into an established research database and categorized according to >400 pre-defined criteria.
UNASSIGNED: There were 265 previously apparently healthy children and 283 with pre-existing, potentially life-limiting, conditions. There were more males than females (M:F 1.4:1), and deaths were more frequent in the winter. Infection was commonest accounting for 43% of all deaths. Non-infectious diseases were identified as cause of death in 28%, and 29% of all deaths were unexplained. There was no significant difference in the proportions of deaths in each category between the previously healthy children and those with pre-existing conditions.
UNASSIGNED: Sudden unexpected death is a rare presentation of death in childhood and those with pre-existing conditions may be more at risk. Standardisation of the post-mortem procedure in such cases may result in more ancillary investigations performed as routine and may reduce the number of cases that are \'unexplained\'.
摘要:
UNASSIGNED:通过回顾性检查单个中心的尸检记录,调查1-18岁儿童自然原因猝死的病因。
UNASSIGNED:检查了548名儿童(1996-2015年)的验尸结果。将详细信息输入已建立的研究数据库,并根据>400预定义的标准进行分类。
UNASISIGNED:有265名以前看起来健康的儿童和283名预先存在的儿童,潜在的生命限制,条件。男性多于女性(M:F1.4:1),冬季死亡更为频繁。感染是最常见的,占所有死亡的43%。非传染性疾病被确定为死亡原因的28%,29%的死亡原因不明。先前健康的儿童和先前存在疾病的儿童之间,每个类别的死亡比例没有显着差异。
UNASSIGNED:突然意外死亡是儿童时期罕见的死亡表现,那些有既往疾病的人可能更有风险。在这种情况下,验尸程序的标准化可能会导致例行进行更多的辅助调查,并可能减少“无法解释”的案件数量。
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