Abstract：
To determine the prevalence and risk factors for cataracts in the Vientiane Province.
We conducted a population-based study of 1264 participants aged ≥40 years of age from urban and rural areas of Vientiane Province. Data collection included demographic information, smoking history, body mass index, blood pressure, history of trauma and dilated lens examination using the World Health Organization WHO Simplified Cataract Grading System. Aphakic and pseudophakic eyes were included as operated cataracts for statistical analysis.
The mean age of the 1264 participants was 57.6 years. The prevalence of any cataract including operated eyes was 46.8% (95% CI: 44.1 - 49.6%): 36.9% nuclear, 21.7% cortical and 10.1% posterior subcapsular cataracts.
The prevalence of cataract in the Vientiane Eye Study is similar compared to the prevalence reported in other studies from Asian regions; however, the median age in this study was low, reflecting the age group of the population and the rapid urbanisation occurring in the Lao People\'s Democratic Republic. A significant association for any cataract was found with elevated blood pressure >148mmHg (OR2.48, 95%CI:1.55 - 3.97, P < 0.01), increasing age (OR1.19, 95%CI:1.17 - 1.22, P < 0.001) and rural inhabitants for cortical cataract (OR1.99, 95%CI:1.37 - 2.90, P < 0.001). An inverse relationship between rural inhabitants with any cataract and nuclear cataract was found (OR 0.63, 95%CI: 0.45 - 0.89, P < 0.01 and OR 0.42, 95%CI: 0.31 - 0.59, P < 0.001) respectively. Nevertheless, cataract remains a high prevalence disease in this population.
We conducted a population-based study of 1264 participants aged ≥40 years of age from urban and rural areas of Vientiane Province. Data collection included demographic information, smoking history, body mass index, blood pressure, history of trauma and dilated lens examination using the World Health Organization WHO Simplified Cataract Grading System. Aphakic and pseudophakic eyes were included as operated cataracts for statistical analysis.
The mean age of the 1264 participants was 57.6 years. The prevalence of any cataract including operated eyes was 46.8% (95% CI: 44.1 - 49.6%): 36.9% nuclear, 21.7% cortical and 10.1% posterior subcapsular cataracts.
The prevalence of cataract in the Vientiane Eye Study is similar compared to the prevalence reported in other studies from Asian regions; however, the median age in this study was low, reflecting the age group of the population and the rapid urbanisation occurring in the Lao People\'s Democratic Republic. A significant association for any cataract was found with elevated blood pressure >148mmHg (OR2.48, 95%CI:1.55 - 3.97, P < 0.01), increasing age (OR1.19, 95%CI:1.17 - 1.22, P < 0.001) and rural inhabitants for cortical cataract (OR1.99, 95%CI:1.37 - 2.90, P < 0.001). An inverse relationship between rural inhabitants with any cataract and nuclear cataract was found (OR 0.63, 95%CI: 0.45 - 0.89, P < 0.01 and OR 0.42, 95%CI: 0.31 - 0.59, P < 0.001) respectively. Nevertheless, cataract remains a high prevalence disease in this population.
摘要：
目的确定万象省白内障的患病率和危险因素。
我们对来自万象省城市和农村地区的1264名年龄≥40岁的参与者进行了一项基于人群的研究。数据收集包括人口统计信息，吸烟史,身体质量指数,血压,使用世界卫生组织WHO简化白内障分级系统进行外伤史和晶状体扩张检查。包括无晶状体和假晶状体眼作为手术白内障进行统计分析。
1264名参与者的平均年龄为57.6岁。包括手术眼在内的任何白内障的患病率为46.8％（95％CI：44.1-49.6％）：36.9％核，21.7%的皮质和10.1%的后囊下白内障。
万象眼科研究中白内障的患病率与亚洲地区其他研究报告的患病率相似；然而，这项研究的平均年龄很低，反映了老挝人民民主共和国人口的年龄组和快速城市化。发现任何白内障与血压升高>148mmHg（OR2.48，95CI：1.55-3.97，P<0.01）存在显着关联，年龄增加（OR1.19，95CI：1.17-1.22，P<0.001），农村居民患有皮质性白内障（OR1.99，95CI：1.37-2.90，P<0.001）。发现农村居民患有白内障和核性白内障之间存在负相关关系（OR分别为0.63，95CI：0.45-0.89，P<0.01和OR0.42，95CI：0.31-0.59，P<0.001）。然而，白内障仍然是该人群中的高患病率疾病。
我们对来自万象省城市和农村地区的1264名年龄≥40岁的参与者进行了一项基于人群的研究。数据收集包括人口统计信息，吸烟史,身体质量指数,血压,使用世界卫生组织WHO简化白内障分级系统进行外伤史和晶状体扩张检查。包括无晶状体和假晶状体眼作为手术白内障进行统计分析。
1264名参与者的平均年龄为57.6岁。包括手术眼在内的任何白内障的患病率为46.8％（95％CI：44.1-49.6％）：36.9％核，21.7%的皮质和10.1%的后囊下白内障。
万象眼科研究中白内障的患病率与亚洲地区其他研究报告的患病率相似；然而，这项研究的平均年龄很低，反映了老挝人民民主共和国人口的年龄组和快速城市化。发现任何白内障与血压升高>148mmHg（OR2.48，95CI：1.55-3.97，P<0.01）存在显着关联，年龄增加（OR1.19，95CI：1.17-1.22，P<0.001），农村居民患有皮质性白内障（OR1.99，95CI：1.37-2.90，P<0.001）。发现农村居民患有白内障和核性白内障之间存在负相关关系（OR分别为0.63，95CI：0.45-0.89，P<0.01和OR0.42，95CI：0.31-0.59，P<0.001）。然而，白内障仍然是该人群中的高患病率疾病。
