PDF(Pubmed)
Abstract：
UNASSIGNED: Systematic reviews have highlighted the lack of evidence on choosing the type of intermittent urinary catheter (IUC) with regard to the occurrence of urinary tract infections (UTIs).
UNASSIGNED: To describe the incidence and frequency of symptoms suggestive of UTIs (ssUTIs) for prelubricated versus hydrophilic IUCs.
UNASSIGNED: An observational study of a patient database compiled by UK general practitioners was conducted.
UNASSIGNED: The primary outcome measures were the proportion of patients with at least one ssUTI (prescription of a nonspecific antibiotic with a UTI-related diagnosis, or prescription of a UTI-specific antibiotic) and the mean number of ssUTIs per affected patient in the 12 mo following the index IUC prescription. Comparable prelubricated (\"PRELUBE\") and hydrophilic (\"HYDRO\") catheter groups were obtained with 1:1 propensity score matching (PSM).
UNASSIGNED: A total of 5296 patients were included (prelubricated: n = 458; hydrophilic: n = 4838). After PSM, the two groups had similar proportions of patients with ssUTIs at baseline. The proportion of patients with ssUTIs during exposure was similar in the PRELUBE (36.9%) and HYDRO groups (41.5%; p = 0.155). However, among patients having used the same type of catheter throughout the exposure period, the proportion with ssUTIs was significantly lower in the PRELUBE group (44.6%, vs 55.0% for HYDRO; p = 0.015), as was the number of ssUTIs per patient (1.3 vs 1.8; p = 0.036).
UNASSIGNED: When choosing a coated IUC, physicians and patients should not rule out PRELUBE IUCs for safety reasons alone.
UNASSIGNED: Using real-world data compiled by UK general practitioners, we described the incidence and frequency of symptoms suggestive of urinary tract infection in people who were using various types of intermittent urinary catheters. When the same type of prelubricated catheter was used throughout the study period, the incidence of these symptoms was lower than for hydrophilic catheters.
UNASSIGNED: To describe the incidence and frequency of symptoms suggestive of UTIs (ssUTIs) for prelubricated versus hydrophilic IUCs.
UNASSIGNED: An observational study of a patient database compiled by UK general practitioners was conducted.
UNASSIGNED: The primary outcome measures were the proportion of patients with at least one ssUTI (prescription of a nonspecific antibiotic with a UTI-related diagnosis, or prescription of a UTI-specific antibiotic) and the mean number of ssUTIs per affected patient in the 12 mo following the index IUC prescription. Comparable prelubricated (\"PRELUBE\") and hydrophilic (\"HYDRO\") catheter groups were obtained with 1:1 propensity score matching (PSM).
UNASSIGNED: A total of 5296 patients were included (prelubricated: n = 458; hydrophilic: n = 4838). After PSM, the two groups had similar proportions of patients with ssUTIs at baseline. The proportion of patients with ssUTIs during exposure was similar in the PRELUBE (36.9%) and HYDRO groups (41.5%; p = 0.155). However, among patients having used the same type of catheter throughout the exposure period, the proportion with ssUTIs was significantly lower in the PRELUBE group (44.6%, vs 55.0% for HYDRO; p = 0.015), as was the number of ssUTIs per patient (1.3 vs 1.8; p = 0.036).
UNASSIGNED: When choosing a coated IUC, physicians and patients should not rule out PRELUBE IUCs for safety reasons alone.
UNASSIGNED: Using real-world data compiled by UK general practitioners, we described the incidence and frequency of symptoms suggestive of urinary tract infection in people who were using various types of intermittent urinary catheters. When the same type of prelubricated catheter was used throughout the study period, the incidence of these symptoms was lower than for hydrophilic catheters.
摘要：
UASSIGNED：系统综述强调了在尿路感染（UTI）的发生方面缺乏选择间歇性导尿管（IUC）类型的证据。
UNASSIGNED：描述提示尿路感染（ssUTIs）的预润滑与亲水性IUC的发生率和频率。
UNASSIGNED：对英国全科医生编制的患者数据库进行观察性研究。
UNASSIGNED：主要结局指标是至少有一种ssUTI（非特异性抗生素处方与UTI相关诊断，或UTI特异性抗生素的处方）以及索引IUC处方后12个月内每位受影响患者的平均ssUTI数量。获得了相当的预润滑（“PRELUBE”）和亲水（“HYDRO”）导管组，其倾向评分匹配（PSM）为1:1。
UNASSIGNED：共纳入5296例患者（预润滑：n=458；亲水：n=4838）。PSM之后,基线时,两组的ssUTIs患者比例相似.暴露期间患有ssUTI的患者比例在PRELUBE（36.9％）和HYDRO组（41.5％；p=0.155）中相似。然而,在暴露期间使用相同类型导管的患者中，在PRELUBE组中，SSUTIs的比例显着降低（44.6%，与HYDRO的55.0%相比；p=0.015)，每个患者的ssUTI数量(1.3vs1.8;p=0.036).
UNASSIGNED：选择涂层IUC时，医生和患者不应仅出于安全原因排除PRELUBEIUC.
UNASSIGNED：使用英国全科医生汇编的真实世界数据，我们描述了在使用各种类型的间歇性导尿管的人群中，提示尿路感染的发生率和症状频率。当在整个研究期间使用相同类型的预润滑导管时，这些症状的发生率低于亲水性导管.
UNASSIGNED：描述提示尿路感染（ssUTIs）的预润滑与亲水性IUC的发生率和频率。
UNASSIGNED：对英国全科医生编制的患者数据库进行观察性研究。
UNASSIGNED：主要结局指标是至少有一种ssUTI（非特异性抗生素处方与UTI相关诊断，或UTI特异性抗生素的处方）以及索引IUC处方后12个月内每位受影响患者的平均ssUTI数量。获得了相当的预润滑（“PRELUBE”）和亲水（“HYDRO”）导管组，其倾向评分匹配（PSM）为1:1。
UNASSIGNED：共纳入5296例患者（预润滑：n=458；亲水：n=4838）。PSM之后,基线时,两组的ssUTIs患者比例相似.暴露期间患有ssUTI的患者比例在PRELUBE（36.9％）和HYDRO组（41.5％；p=0.155）中相似。然而,在暴露期间使用相同类型导管的患者中，在PRELUBE组中，SSUTIs的比例显着降低（44.6%，与HYDRO的55.0%相比；p=0.015)，每个患者的ssUTI数量(1.3vs1.8;p=0.036).
UNASSIGNED：选择涂层IUC时，医生和患者不应仅出于安全原因排除PRELUBEIUC.
UNASSIGNED：使用英国全科医生汇编的真实世界数据，我们描述了在使用各种类型的间歇性导尿管的人群中，提示尿路感染的发生率和症状频率。当在整个研究期间使用相同类型的预润滑导管时，这些症状的发生率低于亲水性导管.
