Abstract：
OBJECTIVE: During maturation, the ossification centers of the proximal humerus form a characteristic pattern consisting of a metaphyseal peak and corresponding epiphyseal valley. The surface topographies of the metaphyseal peak and epiphyseal valley are not well described and may have variation with age and structural importance to the pathogenesis of proximal humeral epiphysiolysis.
METHODS: High-resolution 3-dimensional surface scans of 24 cadaveric proximal humeral epiphyses and metaphyses in specimens aged 3 to 18 years were obtained. Computer modeling software was used to measure the peak height of the metaphysis and maximal depth of the epiphysis relative to a perpendicular line drawn across the proximal humeral physis.
RESULTS: The metaphyseal peak had a mean height of 12.7 ± 1.6 mm while the epiphyseal valley had a mean depth of 13.1 ± 2.1 mm, both consistently positioned in the posterolateral quadrant. Both the absolute metaphyseal peak height (R2 = 0.536; p < 0.001) and absolute epiphyseal valley depth (R2 = 0.524; p < 0.001) increase with advancing age. Multiple linear regression analysis demonstrated that normalized metaphyseal peak height + sex (adjusted R2 = 0.408; p < 0.002) correlated more with age than normalized epiphyseal valley depth + sex (adjusted R2 = 0.128; p < 0.091).
CONCLUSIONS: Prominence of the metaphyseal peak and epiphyseal valley both increase with advancing age, with a lower correlation between normalized sizes with age as compared to the absolute sizes, suggesting that these structures stay relatively proportional with growth.
METHODS: High-resolution 3-dimensional surface scans of 24 cadaveric proximal humeral epiphyses and metaphyses in specimens aged 3 to 18 years were obtained. Computer modeling software was used to measure the peak height of the metaphysis and maximal depth of the epiphysis relative to a perpendicular line drawn across the proximal humeral physis.
RESULTS: The metaphyseal peak had a mean height of 12.7 ± 1.6 mm while the epiphyseal valley had a mean depth of 13.1 ± 2.1 mm, both consistently positioned in the posterolateral quadrant. Both the absolute metaphyseal peak height (R2 = 0.536; p < 0.001) and absolute epiphyseal valley depth (R2 = 0.524; p < 0.001) increase with advancing age. Multiple linear regression analysis demonstrated that normalized metaphyseal peak height + sex (adjusted R2 = 0.408; p < 0.002) correlated more with age than normalized epiphyseal valley depth + sex (adjusted R2 = 0.128; p < 0.091).
CONCLUSIONS: Prominence of the metaphyseal peak and epiphyseal valley both increase with advancing age, with a lower correlation between normalized sizes with age as compared to the absolute sizes, suggesting that these structures stay relatively proportional with growth.
摘要：
目标：在成熟过程中，肱骨近端的骨化中心形成了一个特征性的模式，包括干phy端峰和相应的骨phy谷。干phy端峰和phy谷的表面形貌未得到很好的描述，并且可能随着年龄和结构对肱骨近端上皮溶解的发病机理具有重要意义而变化。
方法：对年龄在3～18岁的24例尸体肱骨近端骨phy和干mis端进行高分辨率三维表面扫描。使用计算机建模软件来测量干is端的峰值高度和骨phy的最大深度，该深度相对于横跨肱骨近端植骨的垂直线。
结果：干phy端峰的平均高度为12.7±1.6mm，而phy端谷的平均深度为13.1±2.1mm，两者始终位于后外侧象限。随着年龄的增长，干phy端绝对峰高度（R2=0.536；p<0.001）和绝对phy谷深度（R2=0.524；p<0.001）均增加。多元线性回归分析表明，标准化干phy端峰高性别（调整后的R2=0.408；p<0.002）与年龄的相关性高于标准化phy谷深度（调整后的R2=0.128；p<0.091）。
结论：干phy端峰和骨phy谷的出现均随年龄增长而增加，与绝对尺寸相比，归一化尺寸与年龄的相关性较低，这表明这些结构与增长保持相对比例。
方法：对年龄在3～18岁的24例尸体肱骨近端骨phy和干mis端进行高分辨率三维表面扫描。使用计算机建模软件来测量干is端的峰值高度和骨phy的最大深度，该深度相对于横跨肱骨近端植骨的垂直线。
结果：干phy端峰的平均高度为12.7±1.6mm，而phy端谷的平均深度为13.1±2.1mm，两者始终位于后外侧象限。随着年龄的增长，干phy端绝对峰高度（R2=0.536；p<0.001）和绝对phy谷深度（R2=0.524；p<0.001）均增加。多元线性回归分析表明，标准化干phy端峰高性别（调整后的R2=0.408；p<0.002）与年龄的相关性高于标准化phy谷深度（调整后的R2=0.128；p<0.091）。
结论：干phy端峰和骨phy谷的出现均随年龄增长而增加，与绝对尺寸相比，归一化尺寸与年龄的相关性较低，这表明这些结构与增长保持相对比例。
