PDF(Pubmed)
Abstract：
To evidently assess the applicability of regulate menstrual cycle (MC) characteristics in Traditional Chinese Medicine (TCM) as an indicator for fertility.
A community-based prospective cohort study was conducted in China. Between January 2010 and December 2012, women who were willing to conceive within 2 years were enrolled in the study. Other than the MC length pattern, a well-adopted MC characteristic, menstrual blood color and clots were specifically concerned for women enrolled. All participants were followed up in 2 years by trained nurses. Pregnancy rate, fecundability odds ratio () and risk of miscarriage were assessed as fertility outcomes.
A total of 2109 women were effectively included in this cohort for analysis. Results show that women with irregular MC length were less likely to achieve conception (= 0.59; 95% = 0.45-0.77, < 0.001). Menstrual blood in bright red color was also associated with decline in likelihood of conception ( = 0.79; 95% = 0.63-0.98, = 0.04). Women with menstrual blood in light red were at higher risk of miscarriage ( = 2.39; 95% = 0.91-6.28, = 0.08). No significant impact was found between menstrual blood clots and fertility outcomes ( = 1.02, 95% = 0.83-1.25, = 0.88; = 1.26 95% = 0.77-2.07, = 0.35).
MC characteristics can be an effective and simple indicator for women\'s fertility. Increasing the knowledge of MC characteristics for women in reproductive ages would bring great benefits to their preconception health conditions.
A community-based prospective cohort study was conducted in China. Between January 2010 and December 2012, women who were willing to conceive within 2 years were enrolled in the study. Other than the MC length pattern, a well-adopted MC characteristic, menstrual blood color and clots were specifically concerned for women enrolled. All participants were followed up in 2 years by trained nurses. Pregnancy rate, fecundability odds ratio () and risk of miscarriage were assessed as fertility outcomes.
A total of 2109 women were effectively included in this cohort for analysis. Results show that women with irregular MC length were less likely to achieve conception (= 0.59; 95% = 0.45-0.77, < 0.001). Menstrual blood in bright red color was also associated with decline in likelihood of conception ( = 0.79; 95% = 0.63-0.98, = 0.04). Women with menstrual blood in light red were at higher risk of miscarriage ( = 2.39; 95% = 0.91-6.28, = 0.08). No significant impact was found between menstrual blood clots and fertility outcomes ( = 1.02, 95% = 0.83-1.25, = 0.88; = 1.26 95% = 0.77-2.07, = 0.35).
MC characteristics can be an effective and simple indicator for women\'s fertility. Increasing the knowledge of MC characteristics for women in reproductive ages would bring great benefits to their preconception health conditions.
摘要：
目的明确评价中医月经周期(MC)特征作为生育指标的适用性。
在中国进行了一项基于社区的前瞻性队列研究。在2010年1月至2012年12月之间，愿意在2年内怀孕的女性被纳入研究。除了MC长度模式，被广泛采用的MC特性，对于入组的女性，月经血液颜色和血凝块是特别关注的。所有参与者均由训练有素的护士在2年内进行随访。怀孕率,受孕能力比值比()和流产风险被评估为生育结局.
共有2109名女性被有效纳入该队列进行分析。结果表明，MC长度不规则的女性不太可能怀孕（=0.59；95％=0.45-0.77，<0.001）。鲜红色的月经血液也与受孕可能性的下降有关（=0.79；95％=0.63-0.98，=0.04）。月经血为浅红色的女性流产的风险较高（=2.39;95％=0.91-6.28，=0.08）。经血凝块与生育结果之间没有显着影响（=1.02，95％=0.83-1.25，=0.88；=1.2695％=0.77-2.07，=0.35）。
MC特征可以成为女性生育能力的有效且简单的指标。增加育龄妇女对MC特征的了解将为其孕前健康状况带来极大的好处。
在中国进行了一项基于社区的前瞻性队列研究。在2010年1月至2012年12月之间，愿意在2年内怀孕的女性被纳入研究。除了MC长度模式，被广泛采用的MC特性，对于入组的女性，月经血液颜色和血凝块是特别关注的。所有参与者均由训练有素的护士在2年内进行随访。怀孕率,受孕能力比值比()和流产风险被评估为生育结局.
共有2109名女性被有效纳入该队列进行分析。结果表明，MC长度不规则的女性不太可能怀孕（=0.59；95％=0.45-0.77，<0.001）。鲜红色的月经血液也与受孕可能性的下降有关（=0.79；95％=0.63-0.98，=0.04）。月经血为浅红色的女性流产的风险较高（=2.39;95％=0.91-6.28，=0.08）。经血凝块与生育结果之间没有显着影响（=1.02，95％=0.83-1.25，=0.88；=1.2695％=0.77-2.07，=0.35）。
MC特征可以成为女性生育能力的有效且简单的指标。增加育龄妇女对MC特征的了解将为其孕前健康状况带来极大的好处。
